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1. (WO2017057973) NOVEL OPHTHALMIC COMPOSITION COMPRISING REBAMIPIDE AND METHOD FOR PREPARING THE SAME
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Pub. No.: WO/2017/057973 International Application No.: PCT/KR2016/011015
Publication Date: 06.04.2017 International Filing Date: 30.09.2016
IPC:
A61K 47/40 (2006.01) ,A61K 31/4704 (2006.01) ,A61K 47/18 (2017.01) ,A61K 9/00 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
30
Macromolecular compounds
36
Polysaccharides; Derivatives thereof
40
Cyclodextrins; Derivatives thereof
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
435
having six-membered rings with one nitrogen as the only ring hetero atom
47
Quinolines; Isoquinolines
4704
2-Quinolinones, e.g. carbostyril
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
06
Organic compounds
16
containing nitrogen
18
Amines; Quaternary ammonium compounds
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
Applicants:
SAMJIN PHARMACEUTICAL CO., LTD. [KR/KR]; 121, Wausan-ro Mapo-gu Seoul 04054, KR
Inventors:
CHO, Eui-Hwan; KR
CHOI, Sung-Ju; KR
LEE, Sung-Woo; KR
SHIN, Hee-Jong; KR
KI, Min-Hyo; KR
CHOI, Mee-Hwa; KR
LEE, Dong-Ha; KR
Agent:
AHN, So Young; KR
Priority Data:
10-2015-013834901.10.2015KR
Title (EN) NOVEL OPHTHALMIC COMPOSITION COMPRISING REBAMIPIDE AND METHOD FOR PREPARING THE SAME
(FR) NOUVELLE COMPOSITION PHARMACEUTIQUE COMPRENANT DU RÉBAMIPIDE ET SON PROCÉDÉ DE PRÉPARATION
Abstract:
(EN) The present disclosure provides a novel ophthalmic composition comprising rebamipide and a method for preparing the same. The ophthalmic composition of the present disclosure maintains its transparency for a long time even in a physiologically neutral to weakly basic pH range that does not injure the cornea and conjunctiva of a patient suffering from dry eye and has improved stability so as not to be re-dispersed.
(FR) La présente invention concerne une nouvelle composition ophtalmique comprenant du rébamipide et un procédé de préparation de celle-ci. La composition ophtalmique de la présente invention conserve sa transparence pendant une longue durée même dans une plage de pH physiologiquement neutre à faiblement basique qui ne lèse pas la cornée et la conjonctive d'un patient souffrant de sécheresse oculaire et présente une stabilité améliorée de manière à ne pas être redispersée.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)