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1. (WO2017057778) USE OF LAMININ 2 FOR DIAGNOSING HEPATOCELLULAR CARCINOMA AND PANCREATIC CANCER
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2017/057778    International Application No.:    PCT/JP2016/079711
Publication Date: 06.04.2017 International Filing Date: 28.09.2016
IPC:
G01N 33/574 (2006.01)
Applicants: ABBOTT JAPAN CO., LTD. [JP/JP]; 3-5-27, Mita, Minato-ku, Tokyo 1086303 (JP).
THE UNIVERSITY OF TOKYO [JP/JP]; 3-1, Hongo 7-chome, Bunkyo-ku, Tokyo 1138654 (JP)
Inventors: YOSHIMURA, Toru; (JP).
YOSHIDA, Eisaku; (JP).
KOSHIKAWA, Naohiko; (JP).
SEIKI, Motoharu; (JP)
Agent: KAWAGUTI & PARTNERS; Shinjuku Front Tower 20F, 2-21-1 Kita-Shinjuku, Shinjuku-ku, Tokyo 1690074 (JP)
Priority Data:
62/233,745 28.09.2015 US
62/295,607 16.02.2016 US
Title (EN) USE OF LAMININ 2 FOR DIAGNOSING HEPATOCELLULAR CARCINOMA AND PANCREATIC CANCER
(FR) PROCÉDÉS DE DIAGNOSTIC DU CARCINOME HÉPATOCELLULAIRE ET DU CANCER DU PANCRÉAS
Abstract: front page image
(EN)Disclosed herein are biomarkers for hepatocellular carcinoma and pancreatic cancer. The biomarkers may be laminin gamma 2 monomer, PIVKA-II, AFP, CEA, CA19-9, or combinations thereof. Also disclosed herein are methods of diagnosing, prognosing, classifying risk, and monitoring progression of hepatocellular carcinoma or pancreatic cancer by the detecting the level of laminin gamma 2 monomer, PIVKA-II, AFP, CEA, CA19-9, or combinations thereof.
(FR)La présente invention concerne des biomarqueurs pour un carcinome hépatocellulaire et un cancer du pancréas. Les biomarqueurs peuvent être un monomère de laminine gamma 2, PIVKA-II, AFP, CEA, CA19-9, ou des combinaisons de ceux-ci. La présente invention concerne également des procédés de diagnostic, de pronostic, de classification du risque et de surveillance de la progression du carcinome hépatocellulaire ou du cancer du pancréas par la détection du taux de monomère de laminine gamma 2, de PIVKA-II, d'AFP, de CEA, de CA19-9, ou des combinaisons de ceux-ci.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)