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1. (WO2017057672) METHOD FOR STABILIZING LUCIFERIN AND METHOD FOR MEASURING BIOLUMINESCENCE

Pub. No.:    WO/2017/057672    International Application No.:    PCT/JP2016/079006
Publication Date: Fri Apr 07 01:59:59 CEST 2017 International Filing Date: Sat Oct 01 01:59:59 CEST 2016
IPC: C12Q 1/66
G01N 33/532
Applicants: EIKEN KAGAKU KABUSHIKI KAISHA
栄研化学株式会社
Inventors: YAMAOKA, Toshihiko
山岡 利彦
Title: METHOD FOR STABILIZING LUCIFERIN AND METHOD FOR MEASURING BIOLUMINESCENCE
Abstract:
The problem to be solved by the present invention is to provide a composition that increases the stability of a luciferin solution. The present invention provides: a method for stabilizing a luciferin solution, said method characterized in that a boronic acid derivative or a salt thereof is made to coexist in the luciferin solution; and a method for suppressing an attenuation or a decrease in the intensity of bioluminescence, said method characterized in that, when carrying out a bioluminescence reaction of luciferase using luciferin as a substrate, a pyrophosphate and a boronic acid derivative or a salt thereof are made to coexist.