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1. (WO2017057344) METHOD FOR REFINING PURE THIOFLAVIN T, METHOD FOR PRODUCING PURE THIOFLAVIN T, COMPOSITION CONTAINING THIOFLAVIN T, AND METHOD FOR DETECTING AMYLOID

Pub. No.:    WO/2017/057344    International Application No.:    PCT/JP2016/078416
Publication Date: Fri Apr 07 01:59:59 CEST 2017 International Filing Date: Wed Sep 28 01:59:59 CEST 2016
IPC: C07D 277/66
G01N 33/52
Applicants: HAMAMATSU PHOTONICS K.K.
浜松ホトニクス株式会社
Inventors: SATOZONO Hiroshi
里園 浩
Title: METHOD FOR REFINING PURE THIOFLAVIN T, METHOD FOR PRODUCING PURE THIOFLAVIN T, COMPOSITION CONTAINING THIOFLAVIN T, AND METHOD FOR DETECTING AMYLOID
Abstract:
The present invention pertains to a method for refining pure thioflavin T, the method being provided with a step for preparing a thioflavin T solution of crude thioflavin T dissolved in a polar solvent, and a step for performing liquid-liquid extraction of the thioflavin T solution using a nonpolar solvent.