WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Options
Query Language
Stem
Sort by:
List Length
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2017/055635 International Application No.: PCT/EP2016/073584
Publication Date: 06.04.2017 International Filing Date: 03.10.2016
IPC:
C07K 14/725 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435
from animals; from humans
705
Receptors; Cell surface antigens; Cell surface determinants
725
T-cell receptors
Applicants: OSPEDALE SAN RAFFAELE S.R.L.[IT/IT]; Via Olgettina 60 20132 Milano (MI), IT
FONDAZIONE CENTRO SAN RAFFAELE[IT/IT]; Via Olgettina 60 20132 Milano (MI), IT
Inventors: CASORATI, Giulia; IT
DELLABONA, Paolo; IT
DE LALLA, Claudia; IT
GARAVAGLIA, Claudio; IT
CONSONNI, Michela; IT
Agent: TRILLAT, Anne-Cécile; IT
CAPASSO, Olga; IT
TURRI, Elisa; IT
Priority Data:
EP15187993.901.10.2015EP
Title (EN) TCR AND USES THEREOF
(FR) TCR ET UTILISATIONS ASSOCIÉES
Abstract:
(EN) The present invention relates to a TCR or functional variant thereof having antigenic specificity for CD1c molecules associated with a self-lipid, preferably (mLPA) or derivative thereof, to relative polypeptide, protein, nucleic acid, recombinant expression vector, host cell, population of cells, antibody and pharmaceutical composition. The present invention also relates to the uses of said TCR and relative products, in particular for use in the treatment and/or prevention of an hematological disorder.
(FR) La présente invention concerne un TCR ou variant fonctionnel de celui-ci ayant une spécificité antigénique pour les molécules CD1c associées à un lipide du soi, de préférence (mLPA) ou un dérivé de celui-ci. La présente invention concerne également un polypeptide, une protéine, un acide nucléique, un vecteur d'expression recombinant, une cellule hôte, une population de cellules, un anticorps et une composition pharmaceutique associés. La présente invention concerne en outre les utilisations dudit TCR et des produits associés, en particulier pour leur utilisation dans le traitement et/ou la prévention d'un trouble hématologique.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)