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1. (WO2017055324) METHODS FOR QUANTIFYING THE POPULATION OF CELLS OF MONOCYTIC ORIGIN IN A TISSUE SAMPLE
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Pub. No.: WO/2017/055324 International Application No.: PCT/EP2016/073055
Publication Date: 06.04.2017 International Filing Date: 28.09.2016
IPC:
C12Q 1/68 (2006.01)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
Q
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1
Measuring or testing processes involving enzymes or micro-organisms; Compositions therefor; Processes of preparing such compositions
68
involving nucleic acids
Applicants:
INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE) [FR/FR]; 101, rue de Tolbiac 75013 Paris, FR
UNIVERSITÉ PARIS DIDEROT - PARIS 7 [FR/FR]; 5, rue Thomas Mann 75013 Paris, FR
UNIVERSITÉ PIERRE ET MARIE CURIE (PARIS 6) [FR/FR]; 4, place Jussieu 75005 Paris, FR
UNIVERSITÉ PARIS DESCARTES [FR/FR]; 12, rue de l'Ecole de Médecine 75006 Paris, FR
LIGUE NATIONALE CONTRE LE CANCER [FR/FR]; 14 rue Corvisart 75013 Paris, FR
ASSISTANCE PUBLIQUE-HÔPITAUX DE PARIS (APHP) [FR/FR]; 3, avenue Victoria 75004 Paris, FR
Inventors:
FRIDMAN, Wolf Herman; FR
DE REYNIES, Aurélien; FR
BECHT, Etienne; FR
Agent:
COLLIN, Matthieu; FR
Priority Data:
EP15306522.229.09.2015EP
EP16305888.612.07.2016EP
Title (EN) METHODS FOR QUANTIFYING THE POPULATION OF CELLS OF MONOCYTIC ORIGIN IN A TISSUE SAMPLE
(FR) PROCÉDÉS DE QUANTIFICATION DE LA POPULATION DE CELLULES D’ORIGINE MONOCYTAIRE DANS UN PRÉLÈVEMENT DE TISSU
Abstract:
(EN) The present invention relates to methods for quantifying the population of cells of monocytic origin in a tissue sample. In particular, the present invention relates to a method for quantifying the population of cells of monocytic origin in a tissue sample obtained from a subject comprising determining the expression level of at least one gene selected from the group consisting of CSF1R, ADAP2, RASSF4, FPR3, TFEC, PLA2G7 and KYNU.
(FR) La présente invention concerne des procédés de quantification de la population de cellules d’origine monocytaire dans un prélèvement de tissu. En particulier, la présente invention concerne un procédé de quantification de la population de cellules d’origine monocytaire dans un prélèvement de tissu obtenu auprès d’un sujet comprenant la détermination du niveau d’expression d’au moins un gène sélectionné dans le groupe constitué de CSF1R, ADAP2, RASSF4, FPR3, TFEC, PLA2G7 et KYNU.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)