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1. (WO2017055321) METHODS FOR QUANTIFYING THE POPULATION OF FIBROBLASTS IN A TISSUE SAMPLE

Pub. No.:    WO/2017/055321    International Application No.:    PCT/EP2016/073052
Publication Date: Fri Apr 07 01:59:59 CEST 2017 International Filing Date: Thu Sep 29 01:59:59 CEST 2016
IPC: C12Q 1/68
Applicants: INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE)
UNIVERSITÉ PARIS DIDEROT - PARIS 7
UNIVERSITÉ PIERRE ET MARIE CURIE (PARIS 6)
UNIVERSITÉ PARIS DESCARTES
LIGUE NATIONALE CONTRE LE CANCER
ASSISTANCE PUBLIQUE-HÔPITAUX DE PARIS (APHP)
Inventors: FRIDMAN, Wolf, Herman
DE REYNIES, Aurélien
BECHT, Etienne
Title: METHODS FOR QUANTIFYING THE POPULATION OF FIBROBLASTS IN A TISSUE SAMPLE
Abstract:
The present invention relates to methods for quantifying the population of fibroblasts in a tissue sample. In particular, the present invention relates to a method for quantifying the population of fibroblasts in a tissue sample obtained from a subject comprising determining the expression level of at least one gene selected from the group consisting of DCN, COL6A2, 10 COL6A1, COL3A1, COL1A1, PAMR1, TAGLN and GREM1.