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1. (WO2017041142) POLYMER CONJUGATE COMPRISING A BIOACTIVE AGENT

Pub. No.:    WO/2017/041142    International Application No.:    PCT/AU2016/050850
Publication Date: Fri Mar 17 00:59:59 CET 2017 International Filing Date: Sat Sep 10 01:59:59 CEST 2016
IPC: A61K 31/19
A61K 31/4192
A61K 31/4196
A61K 31/47
A61P 29/00
Applicants: POLYACTIVA PTY LTD
Inventors: BIRKETT, Stephen, Lonsdale
DONOHUE, Andrew, Craig
D'SOUZA, Asha, Marina
NG, Sara, Man Yee
SULISTIO, Adrian
TAIT, Russell, John
VALADE, David
NAYLOR, Alan
Title: POLYMER CONJUGATE COMPRISING A BIOACTIVE AGENT
Abstract:
The present invention relates in general to polymer-bioactive agent conjugates for delivering a bioactive agent to a subject. The polymer-bioactive agent conjugates contain triazole moieties in the polymer backbone and a bioactive moiety selected from quinolones, NSAIDs and mixtures thereof. The present invention also relates to methods for preparing the polymer conjugates using click cycloaddition chemical reactions, to monomer-bioactive agent conjugates suitable for preparing the polymer conjugates, and to pharmaceutical products comprising the polymer conjugates for the post-surgical care to treat or prevent infections, provide analgesia and treat inflammation.