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1. (WO2017041063) COMPOSITIONS AND METHODS FOR IDENTIFYING GENETIC PREDISPOSITION TO OBESITY AND FOR ENHANCING ADIPOGENESIS

Pub. No.:    WO/2017/041063    International Application No.:    PCT/US2016/050304
Publication Date: Fri Mar 10 00:59:59 CET 2017 International Filing Date: Sun Sep 04 01:59:59 CEST 2016
IPC: C12N 5/0775
C12N 15/00
Applicants: BROWN UNIVERSITY
UNIVERSITY OF CINCINNATI
UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION
MCGARVEY, Stephen, T.
DEKA, Ranjan
HAWLEY, Nicola, L.
MINSTER, Ryan, Lee
URBAN, Zsolt
SU, Chi-Ting
KERSHAW, Erin, Elizabeth
Inventors: MCGARVEY, Stephen, T.
DEKA, Ranjan
HAWLEY, Nicola, L.
MINSTER, Ryan, Lee
URBAN, Zsolt
SU, Chi-Ting
KERSHAW, Erin, Elizabeth
WEEKS, Daniel, E.
Title: COMPOSITIONS AND METHODS FOR IDENTIFYING GENETIC PREDISPOSITION TO OBESITY AND FOR ENHANCING ADIPOGENESIS
Abstract:
The present invention provides compositions and methods for identifying a subject as having a genetic predisposition to obesity or at risk of developing obesity. The present invention also provides compositions and methods for expressing a CREBRF polypeptide of the invention in a cell or precursor thereof and cells expressing a nucleic acid molecule encoding a CREBRF polypeptide of the invention.