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1. (WO2017041054) COMPOSITIONS FOR IMPROVED NRF2 ACTIVATION AND METHODS OF THEIR USE
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Pub. No.: WO/2017/041054 International Application No.: PCT/US2016/050292
Publication Date: 09.03.2017 International Filing Date: 02.09.2016
IPC:
A61P 25/00 (2006.01) ,A61K 31/426 (2006.01) ,A61K 31/4439 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25
Drugs for disorders of the nervous system
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
41
having five-membered rings with two or more ring hetero atoms, at least one of which is nitrogen, e.g. tetrazole
425
Thiazoles
426
1,3-Thiazoles
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
435
having six-membered rings with one nitrogen as the only ring hetero atom
44
Non-condensed pyridines; Hydrogenated derivatives thereof
4427
containing further heterocyclic ring systems
4439
containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
Applicants:
PATHWAYS BIOSCIENCE, LLC [US/US]; 12635 E. Montview Blvd., Suite 130 Aurora, CO 80045, US
Inventors:
HYBERTSON, Brooks, Michael; US
MCCORD, Joe, Milton; US
Agent:
CHEN, Peter; US
BARONE, Stephen, B.; US
BYORICK, E, Michael; US
BARTON, Steven, K.; US
ANIS, Hissan; US
Priority Data:
62/214,17503.09.2015US
62/355,81028.06.2016US
Title (EN) COMPOSITIONS FOR IMPROVED NRF2 ACTIVATION AND METHODS OF THEIR USE
(FR) COMPOSITIONS POUR L'ACTIVATION DE NRF2 AMÉLIORÉE ET LEURS MÉTHODES D'UTILISATION
Abstract:
(EN) Disclosed here are compositions and methods for preventing or treating certain health conditions associated with inflammation or oxidative stress. These compositions are prepared from ingredients containing phytochemicals that activate the Nrf2 pathways. Synergistic effects of the different phytochemicals are also disclosed.
(FR) L'invention concerne des compositions et des méthodes pour la prévention ou le traitement de certaines affections associées à l'inflammation ou à un stress oxydatif. Ces compositions sont préparées à partir d'ingrédients comprenant des composés phytochimiques qui activent les voies de Nrf2. Des effets synergiques des différents composés phytochimiques sont également décrits.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)