Search International and National Patent Collections

1. (WO2017041050) INTRACELLULAR DELIVERY OF BIOMOLECULES MEDIATED BY A SURFACE WITH PORES

Pub. No.:    WO/2017/041050    International Application No.:    PCT/US2016/050287
Publication Date: Fri Mar 10 00:59:59 CET 2017 International Filing Date: Sat Sep 03 01:59:59 CEST 2016
IPC: C12M 35/04
Applicants: SQZ BIOTECHNOLOGIES COMPANY
Inventors: GILBERT, Jonathan, B.
FREW, Kirubel
BERNSTEIN, Howard
SHAREI, Armon, R.
Title: INTRACELLULAR DELIVERY OF BIOMOLECULES MEDIATED BY A SURFACE WITH PORES
Abstract:
The present disclosure pertains to methods and devices for delivering a compound into a cell, including passing a cell suspension through a surface containing pores, wherein the pores deform the cell thereby causing a perturbation of the cell such that the compound enters the cell, wherein the cell suspension is contacted with the compound.