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1. (WO2017041033) MESOPOROUS SILICA NANOPARTICLES AND SUPPORTED LIPID BI-LAYER NANOPARTICLES FOR BIOMEDICAL APPLICATIONS

Pub. No.:    WO/2017/041033    International Application No.:    PCT/US2016/050260
Publication Date: Fri Mar 10 00:59:59 CET 2017 International Filing Date: Sat Sep 03 01:59:59 CEST 2016
IPC: A61K 9/51
B82Y 5/00
B82Y 40/00
A61P 31/00
A61P 37/00
Applicants: BRINKER, C. Jeffrey
DURFEE, Paul N.
TOWNSON, Jason
LIN, Yu-Shen
CHOU, Stanley Shihyao
ERSTLING, Jacob
Inventors: BRINKER, C. Jeffrey
DURFEE, Paul N.
TOWNSON, Jason
LIN, Yu-Shen
CHOU, Stanley Shihyao
ERSTLING, Jacob
Title: MESOPOROUS SILICA NANOPARTICLES AND SUPPORTED LIPID BI-LAYER NANOPARTICLES FOR BIOMEDICAL APPLICATIONS
Abstract:
The present disclosure is directed to methods of producing monosized protocells from monosized mesoporous silica nanoparticles (mMSNPs) and their use for targeted drug delivery formulations and systems and for biomedical applications. The present disclosure is also directed in part to a multilamellar or unilamellar protocell vaccine to deliver full length viral protein and/or plasmid encoded viral protein to antigen presenting cells (APCs) in order to induce an immunogenic response to a virus.