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1. (WO2017040990) PEPTIDOMIMETIC MACROCYCLES AND USES THEREOF
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Pub. No.: WO/2017/040990 International Application No.: PCT/US2016/050194
Publication Date: 09.03.2017 International Filing Date: 02.09.2016
IPC:
A61K 38/12 (2006.01) ,A61P 35/00 (2006.01)
[IPC code unknown for A61K 38/12][IPC code unknown for A61P 35]
Applicants:
AILERON THERAPEUTICS, INC. [US/US]; 281 Albany Street Cambridge, Massachusetts 02139, US
Inventors:
AIVADO, Manuel; US
GUERLAVAIS, Vincent; US
OLSON, Karen; US
Agent:
MCANDREW, Christopher W.; US
Priority Data:
62/214,14203.09.2015US
62/310,25418.03.2016US
62/344,65102.06.2016US
62/344,79102.06.2016US
Title (EN) PEPTIDOMIMETIC MACROCYCLES AND USES THEREOF
(FR) MACROCYCLES PEPTIDOMIMÉTIQUES ET LEURS UTILISATIONS
Abstract:
(EN) Provided herein are peptidomimetic macrocycles and methods of using such macrocycles for the treatment of disease. Also provided here in are methods of using such macrocycles in combination with at least one additional pharmaceutically active agent for treatment of disorders, for example for treatment of cancer.
(FR) La présente invention concerne des macrocycles peptidomimétiques et des méthodes d'utilisation desdits macrocycles pour le traitement de maladies. L'invention concerne également des méthodes d'utilisation desdits macrocycles en combinaison avec au moins un agent pharmaceutiquement actif supplémentaire pour le traitement de troubles, par exemple pour le traitement du cancer.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)