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1. (WO2017040958) QUALITY CONTROL FOR IMPROVED PRODUCT BIOSYNTHESIS

Pub. No.:    WO/2017/040958    International Application No.:    PCT/US2016/050146
Publication Date: Fri Mar 10 00:59:59 CET 2017 International Filing Date: Sat Sep 03 01:59:59 CEST 2016
IPC: C12Q 1/68
C12N 15/00
C12N 15/09
C12P 13/22
Applicants: WASHINGTON UNIVERSITY
Inventors: ZHANG, Fuzhong
XIAO, Yi
Title: QUALITY CONTROL FOR IMPROVED PRODUCT BIOSYNTHESIS
Abstract:
Systems, methods, and host cells utilizing a PopQC construct for enhancing product biosynthesis by exploitation of non-genetic cell-to-cell variation, wherein the PopQC construct includes at least a product-responsive biosensor and a selection gene..