Search International and National Patent Collections

1. (WO2017040844) TOPICAL ANTIVIRAL COMPOSITIONS

Pub. No.:    WO/2017/040844    International Application No.:    PCT/US2016/049982
Publication Date: Fri Mar 10 00:59:59 CET 2017 International Filing Date: Fri Sep 02 01:59:59 CEST 2016
IPC: A61K 35/52
A61P 31/12
Applicants: TOPICAL REMEDY, LLC
Inventors: KONOWALCHUK, Thomas W.
Title: TOPICAL ANTIVIRAL COMPOSITIONS
Abstract:
In various embodiments compositions that inactivates a virus or inhibit replication of a virus are provided where the compositions comprise a C1-C10 alcohol; an acid selected from the group consisting of gallic acid, methyl gallate, 3, 4-dihydroxy benzoic acid, p-hydroxy benzoic acid, vanillic acid, p-coumaric acid, ferulic acid, syringic acid, salicylic acid, luteic acid, and eudesmic acid; and a pharmaceutically acceptable carrier; where the pH of said composition is pH 4.5 or lower. In certain embodiments the alcohol comprises one or more alcohols selected from the group consisting of ethanol, ethanol, 2-propanol, 1-propanol, 2,3-butanediol, 1,2-butanediol, 1,3-butanediol, and 1,4-butanediol, butyl alcohol (including n-butanol, sec-butanol, isobutanol, tert-butanol), pentanol, hexadecan-1-ol, ethane-1,2-diol, propane-1,2-diol, propane-1,2,3-triol, butane-1,2,3,4-tetraol, pentane-1,2,3,4,5-pentol, hexane-1,2,3,4,5,6-hexol, heptane-1,2,3,4,5,6,7-heptol, prop-2-ene-1-ol, 3,7-dimethylocta-2,6-dien-1-ol, prop-2-in-1-ol, cyclohexane-1,2,3,4,5,6-hexol, and 2-(2-propyl)-5-methyl-cyclohexane-1-ol.