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1. (WO2017040660) COMBINATION THERAPY FOR TREATMENT OF DISEASE

Pub. No.:    WO/2017/040660    International Application No.:    PCT/US2016/049697
Publication Date: Fri Mar 10 00:59:59 CET 2017 International Filing Date: Thu Sep 01 01:59:59 CEST 2016
IPC: A61K 39/00
A61K 39/395
A61P 35/00
A61P 37/02
C07K 16/46
C12N 15/09
Applicants: ONCOMED PHARMACEUTICALS, INC.
Inventors: HOEY, Timothy Charles
CAIN, Jennifer Anne
Title: COMBINATION THERAPY FOR TREATMENT OF DISEASE
Abstract:
The present invention provides methods comprising combination therapy for modulating immune responses, for inhibiting tumor growth, and/or for treating cancer. In particular, the present invention provides RSPO or LGR antagonists in combination with immunotherapeutic agents for the treatment of cancer and other diseases.