Some content of this application is unavailable at the moment.
If this situation persist, please contact us atFeedback&Contact
1. (WO2017040526) SPLICE VARIANTS ASSOCIATED WITH NEOMORPHIC SF3B1 MUTANTS
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2017/040526 International Application No.: PCT/US2016/049490
Publication Date: 09.03.2017 International Filing Date: 30.08.2016
IPC:
C12Q 1/68 (2006.01)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
Q
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1
Measuring or testing processes involving enzymes or micro-organisms; Compositions therefor; Processes of preparing such compositions
68
involving nucleic acids
Applicants:
EISAI R&D MANAGEMENT CO., LTD. [JP/JP]; 6-10 Koishikawa, 4-chome Bunkyo-ku, Tokyo, 112-8088, JP
Inventors:
YU, Lihua; US
LIM, Kian, Huat; US
FEALA, Jacob, D.; US
BUONAMICI, Silvia; US
MIZUI, Yoshiharu; US
SMITH, Peter, G.; US
ZHU, Ping; US
PARK, Eunice, Sun; US
SEILER, Michael, W.; US
FEKKES, Marco, Peter; US
Agent:
FERGUSON, Mary, K.; US
Priority Data:
62/212,87601.09.2015US
Title (EN) SPLICE VARIANTS ASSOCIATED WITH NEOMORPHIC SF3B1 MUTANTS
(FR) VARIANTS D'ÉPISSAGE ASSOCIÉS À DES MUTANTS DE SF3B1 NÉOMORPHES
Abstract:
(EN) Splice variants associated with neomorphic SF3B1 mutations are described herein. This application also relates to methods of detecting the described splice variants, and uses for diagnosing cancer, evaluating modulators of SF3B1, and methods of treating cancer associated with mutations in SF3B 1.
(FR) L'invention concerne des variants d'épissage associés à des mutations de SF3B1 néomorphes. L'invention concerne également des procédés de détection desdits variants d'épissage, et des utilisations pour diagnostiquer un cancer, évaluer des modulateurs de SF3B1, ainsi que des procédés de traitement d'un cancer associé à des mutations chez SF3B1.
front page image
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)