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1. (WO2017040520) MOLECULAR METHODS FOR ASSESSING UROTHELIAL DISEASE
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Pub. No.: WO/2017/040520 International Application No.: PCT/US2016/049483
Publication Date: 09.03.2017 International Filing Date: 30.08.2016
IPC:
C12N 15/10 (2006.01) ,C12Q 1/68 (2006.01) ,G01N 33/48 (2006.01)
[IPC code unknown for C12N 15/10][IPC code unknown for C12Q 1/68][IPC code unknown for G01N 33/48]
Applicants:
HITACHI CHEMICAL CO., LTD. [JP/JP]; 9-2, Marunouchi 1-chome Chiyoda-ku Tokyo, 100-6606, JP
HITACHI CHEMICAL CO. AMERICA, LTD. [US/US]; 2150 North First Street, Suite 350 San Jose, California, 95131, US
CITY OF SAPPORO [JP/JP]; 1-ko-i-1, Kita 1-jo Nishi 2-chome Chuo-ku, Sapporo-shi Hokkaido 060-8611, JP
Inventors:
MURAKAMI, Taku; US
YAMAMOTO, Cindy; US
MITSUHASHI, Masato; US
HARADA, Hiroshi; JP
Agent:
ALTMAN, Daniel, E.; US
Priority Data:
62/212,50131.08.2015US
62/252,25706.11.2015US
62/331,24103.05.2016US
Title (EN) MOLECULAR METHODS FOR ASSESSING UROTHELIAL DISEASE
(FR) MÉTHODES MOLÉCULAIRES POUR ÉVALUER UNE MALADIE UROTHÉLIALE
Abstract:
(EN) The present disclosure relates to methods of collecting exosomes and microvesicles (EMV) from urine, isolating corresponding mRNA, and analyzing expression patterns in order to diagnose and treat various urothelial cancers. In particular, various expression patterns are analyzed through a unique diagnostic formula.
(FR) La présente invention concerne des méthodes de collecte d'exosomes et de microvésicules à partir de l'urine, ainsi que d'isolement de l'ARNm correspondant et d’analyse de profils d’expression en vue du diagnostic et du traitement de divers cancers urothéliaux. En particulier, divers profils d'expression sont analysés par l'intermédiaire d'une formule de diagnostic unique.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)