Search International and National Patent Collections

1. (WO2017040515) MOLECULAR METHODS FOR ASSESSING POST KIDNEY TRANSPLANT COMPLICATIONS

Pub. No.:    WO/2017/040515    International Application No.:    PCT/US2016/049473
Publication Date: Fri Mar 10 00:59:59 CET 2017 International Filing Date: Wed Aug 31 01:59:59 CEST 2016
IPC: C12N 15/10
C12Q 1/68
G01N 33/48
Applicants: HITACHI CHEMICAL CO., LTD.
HITACHI CHEMICAL CO. AMERICA, LTD.
CITY OF SAPPORO
Inventors: MURAKAMI, Taku
YAMAMOTO, Cindy
MITSUHASHI, Masato
HARADA, Hiroshi
Title: MOLECULAR METHODS FOR ASSESSING POST KIDNEY TRANSPLANT COMPLICATIONS
Abstract:
The present disclosure relates to methods of collecting exosomes and microvesicles (EMV) from urine, isolating corresponding mRNA, and analyzing expression patterns in order to diagnose and treat various post-kidney transplant complications. In particular, annexin1 mRNA expression patterns are analyzed through a unique diagnostic formula.