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1. (WO2017040349) PROTEIN PROXIMITY ASSAY IN FORMALIN FIXED PAFFAFIN EMBEDDED TISSUE USING CAGED HAPTENS
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Pub. No.: WO/2017/040349 International Application No.: PCT/US2016/049153
Publication Date: 09.03.2017 International Filing Date: 26.08.2016
IPC:
G01N 33/58 (2006.01) ,G01N 33/53 (2006.01)
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
58
involving labelled substances
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53
Immunoassay; Biospecific binding assay; Materials therefor
Applicants:
VENTANA MEDICAL SYSTEMS, INC. [US/US]; 1910 E. Innovation Park Drive Tucson, AZ 85755, US
Inventors:
BELOSLUDTSEV, Yuri; US
DEGEER, Traci, D.; US
FRENCH, Wendy, J.; US
HAO, Junshan; US
KELLY, Brian, Daniel; US
MURILLO, Adrian; US
POLASKE, Nathan, Walter; US
Agent:
CARDEN, Kellie, L.; US
KOHLI, Vineet; US
REHMS, Aden, A.; US
KOGAN, Daniel; US
JONES, Bryan, W.; US
Priority Data:
62/211,59028.08.2015US
62/301,48929.02.2016US
Title (EN) PROTEIN PROXIMITY ASSAY IN FORMALIN FIXED PAFFAFIN EMBEDDED TISSUE USING CAGED HAPTENS
(FR) DOSAGE DE PROXIMITÉ POUR LA DÉTECTION DE PROTÉINES DANS UN TISSU ENROBÉ DE PARAFFINE ET FIXÉ AVEC DE LA FORMALINE AU MOYEN DE HAPTÈNES EN CAGE
Abstract:
(EN) Disclosed herein are caged haptens and caged hapten-antibody conjugates useful for enabling the detection of targets located proximally to each other in a sample.
(FR) L'invention concerne des haptènes en cage et des conjugués haptène-anticorps en cage utiles pour permettre la détection de cibles situées de manière proximale les unes par rapport aux autres dans un échantillon.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)