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1. (WO2017040341) RAPAMYCIN ANALOGS SHOWING IMPROVED mTORC1 SPECIFICITY

Pub. No.:    WO/2017/040341    International Application No.:    PCT/US2016/049124
Publication Date: Fri Mar 10 00:59:59 CET 2017 International Filing Date: Sat Aug 27 01:59:59 CEST 2016
IPC: C07D 498/18
A61K 31/436
A61K 45/06
Applicants: BUCK INSTITUTE FOR RESEARCH ON AGING
DELOS PHARMACEUTICALS INC.
GREGORY, Matthew Alan
MOSS, Steven
VELARDE, Michael
POWERS, Timothy
TZANNIS, Stelios
Inventors: GREGORY, Matthew Alan
MOSS, Steven
VELARDE, Michael
POWERS, Timothy
TZANNIS, Stelios
Title: RAPAMYCIN ANALOGS SHOWING IMPROVED mTORC1 SPECIFICITY
Abstract:
In various embodiments novel rapamycin analogs are provides that show improved mTORC1 specificity.