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1. (WO2017040329) PEPTIDES BINDING TO BFL-1
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Pub. No.: WO/2017/040329 International Application No.: PCT/US2016/049095
Publication Date: 09.03.2017 International Filing Date: 26.08.2016
IPC:
A61K 38/12 (2006.01) ,C07K 14/00 (2006.01)
[IPC code unknown for A61K 38/12][IPC code unknown for C07K 14]
Applicants:
DANA-FARBER CANCER INSTITUTE, INC. [US/US]; 450 Brookline Avenue Boston, Massachusetts 02215-5450, US
Inventors:
WALENSKY, Loren D.; US
BIRD, Gregory H.; US
Agent:
KOIPALLY, Joseph J.; US
ZHANG, Tony; US
Priority Data:
62/211,68028.08.2015US
Title (EN) PEPTIDES BINDING TO BFL-1
(FR) PEPTIDES SE LIANT À BFL -1
Abstract:
(EN) This disclosure features stapled peptide inhibitors (e.g., cysteine-reactive stapled peptides) of the anti-apoptotic protein, BFL-1, and methods of using same in the treatment of BFL-1 expressing cancers.
(FR) La présente invention concerne des inhibiteurs peptidiques agrafés (par exemple, des peptides agrafés réagissant avec la cystéine) de la protéine anti-apoptotique, BFL -1, et des procédés d'utilisation de ceux-ci dans le traitement de cancers exprimant la protéine BFL-1.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)