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1. (WO2017040175) ADJUNCTS FOR SURGICAL DEVICES INCLUDING AGONISTS AND ANTAGONISTS

Pub. No.:    WO/2017/040175    International Application No.:    PCT/US2016/048578
Publication Date: Fri Mar 10 00:59:59 CET 2017 International Filing Date: Fri Aug 26 01:59:59 CEST 2016
IPC: A61L 27/34
A61L 27/48
A61L 27/54
A61L 27/58
A61B 17/072
Applicants: ETHICON LLC
Inventors: WIDENHOUSE, Tamara S
HENDERSON, Cortney E.
SHELTON, IV, Frederick E.
HARRIS, Jason L.
Title: ADJUNCTS FOR SURGICAL DEVICES INCLUDING AGONISTS AND ANTAGONISTS
Abstract:
Adjuncts for surgical devices including agonists and antagonists are provided. In general, an implantable adjunct can have two or more medicants releasably disposed therein that are each releasable from the adjunct. At least one of the medicants can include an agonist configured to encourage a physiological response, and at least one of the medicants can include an antagonist configured to discourage the physiological response encouraged by the agonist. The physiological response can include an aspect of wound healing such that the aspect of wound healing may be both encouraged by and discouraged by the adjunct. The adjunct having one or more agonists and one or more antagonists releasably disposed therein can be configured to be applied to tissue by a surgical stapler in conjunction with staples.