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1. (WO2017040141) MATRIX METALLOPROTEINASE INHIBITING ADJUNCTS FOR SURGICAL DEVICES
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Pub. No.: WO/2017/040141 International Application No.: PCT/US2016/048366
Publication Date: 09.03.2017 International Filing Date: 24.08.2016
IPC:
A61L 27/18 (2006.01) ,A61L 27/34 (2006.01) ,A61L 27/54 (2006.01) ,A61L 27/58 (2006.01) ,A61B 17/072 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
L
METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
27
Materials for prostheses or for coating prostheses
14
Macromolecular materials
18
obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
L
METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
27
Materials for prostheses or for coating prostheses
28
Materials for coating prostheses
34
Macromolecular materials
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
L
METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
27
Materials for prostheses or for coating prostheses
50
Materials characterised by their function or physical properties
54
Biologically active materials, e.g. therapeutic substances
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
L
METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
27
Materials for prostheses or for coating prostheses
50
Materials characterised by their function or physical properties
58
Materials at least partially resorbable by the body
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
B
DIAGNOSIS; SURGERY; IDENTIFICATION
17
Surgical instruments, devices or methods, e.g. tourniquets
03
for closing wounds, or holding wounds closed, e.g. surgical staples; Accessories for use therewith
068
Surgical staplers
072
for applying a row of staples in a single action
Applicants:
ETHICON LLC [US/US]; #475 Street C, Suite 401 Los Frailes Industrial Park Guaynabo, Puerto Rico 00969, US
Inventors:
WIDENHOUSE, Tamara S; US
SHELTON, IV, Frederick E.; US
HARRIS, Jason L.; US
Agent:
SHIRTZ, Joseph F.; US
REINHARDT, Hilary A.; US
Priority Data:
14/840,40631.08.2015US
Title (EN) MATRIX METALLOPROTEINASE INHIBITING ADJUNCTS FOR SURGICAL DEVICES
(FR) AUXILIAIRES INHIBANT LA MÉTALLOPROTÉINASE MATRICIELLE POUR DISPOSITIFS CHIRURGICAUX
Abstract:
(EN) Various exemplary matrix metalloproteinase (MMP) inhibiting adjuncts for surgical devices are provided. In general, an implantable adjunct can be configured to be applied to tissue by a surgical stapler in conjunction with staples. The adjunct can have at least one medicant releasably retained therein that is configured to reduce a length of the epithelialization process. In other words, the at least one medicant releasably retained in the adjunct can be configured to speed up an inflammation stage of wound healing and/or a proliferation stage of wound healing and, accordingly, reduce an amount of time before a remodeling stage of wound healing begins. The at least one medicant can be configured to be released along the staple line defined by the staples.
(FR) L'invention concerne divers exemples d'auxiliaires inhibant la métalloprotéinase matricielle (MMP) pour des dispositifs chirurgicaux. En général, un auxiliaire implantable peut être conçu pour être appliqué au tissu par une agrafeuse chirurgicale en association avec des agrafes. L'auxiliaire peut contenir un ou plusieurs médicaments retenus avec faculté de libération à l'intérieur qui sont conçus pour réduire la durée du processus d'épithélialisation. En d'autres termes, le ou les médicaments retenus avec faculté de libération à l'intérieur peuvent être conçus pour accélérer une étape d'inflammation de la cicatrisation d'une plaie et/ou un stade de la prolifération de la cicatrisation d'une plaie et, en conséquence, réduire la durée avant le début d'une étape de remodelage de la cicatrisation d'une plaie. Le ou les médicaments peuvent être conçus pour être libérés le long de la ligne d'agrafes définie par les agrafes.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)