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1. (WO2017040113) ADJUNCT MATERIAL TO PROVIDE HETEROGENEOUS DRUG ELUTION

Pub. No.:    WO/2017/040113    International Application No.:    PCT/US2016/048168
Publication Date: Fri Mar 10 00:59:59 CET 2017 International Filing Date: Wed Aug 24 01:59:59 CEST 2016
IPC: A61L 31/16
A61B 17/00
Applicants: ETHICON LLC
Inventors: HARRIS, Jason L.
WIDENHOUSE, Tamara S
VENDELY, Michael J.
SHELTON, IV, Frederick E.
Title: ADJUNCT MATERIAL TO PROVIDE HETEROGENEOUS DRUG ELUTION
Abstract:
Adjunct material to provide drug elution is a variety of different temporal and/or spatial patterns is provided. In general, a biocompatible adjunct having a plurality of distinct regions having a plurality of distinct regions is configured to be delivered to tissue by deployment of staples in a cartridge body of a surgical stapler. Each of the distinct regions can be disposed at a different location on the adjunct material and can have a different adjunct construction. At least two of the regions releasably retain at least one medicant and each of the at least one medicants is releasable from one of the regions in a non-homogeneous manner with respect to at least one of time of release and location of release.