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1. (WO2017039761) ACOUSTIC PERFUSION DEVICES

Pub. No.:    WO/2017/039761    International Application No.:    PCT/US2016/029382
Publication Date: Fri Mar 10 00:59:59 CET 2017 International Filing Date: Wed Apr 27 01:59:59 CEST 2016
IPC: C12M 1/00
B01D 43/00
B01D 21/28
C12M 1/26
Applicants: FLODESIGN SONICS, INC.
Inventors: LIPKENS, Bart
MILLER, Erik
ROSS-JOHNSRUD, Benjamin
PRESZ, JR., Walter M.
CHITALE, Kedar
KENNEDY, III, Thomas J.
WINIARSKI, Lauryn
Title: ACOUSTIC PERFUSION DEVICES
Abstract:
Acoustic perfusion devices for separating biological cells from other material in a fluid mixture are disclosed. The devices include an inlet port, an outlet port, and a collection port that are connected to an acoustic chamber. An ultrasonic transducer creates an acoustic standing wave in the acoustic chamber that permits a continuous flow of fluid to be recovered through the collection port while keeping the biological cells within the acoustic chamber to be returned to the bioreactor from which the fluid mixture is being drawn.