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1. (WO2017039673) IMPROVED METHOD FOR PREPARATIVE AND COMMERCIAL SCALE REVERSE PHASE LIQUID CHROMATOGRAPHY

Pub. No.:    WO/2017/039673    International Application No.:    PCT/US2015/048356
Publication Date: Fri Mar 10 00:59:59 CET 2017 International Filing Date: Fri Sep 04 01:59:59 CEST 2015
IPC: G01N 30/46
Applicants: HYGEIA INDUSTRIES, INC.
Inventors: BELLAFIORE, Lou
HENRETTA, Kevin
GLICKEN, Ed
Title: IMPROVED METHOD FOR PREPARATIVE AND COMMERCIAL SCALE REVERSE PHASE LIQUID CHROMATOGRAPHY
Abstract:
Methods and apparatus are provided for separating compounds from natural and synthetic feedstocks using reverse phase liquid chromatography. Reverse phase separation is conducted on short media beds in a multi-stage process. The present technology relates separating compounds from natural and synthetic feedstocks using reverse phase liquid chromatography, that can be done on a commercial scale. Most commercial scale chromatographic separation of natural and synthetic oils uses normal phase media with highly flammable and toxic solvents. The present technology uses primarily alcohols and water as solvents, which help provide a safer workplace, safer products and reduced environmental impact.