Search International and National Patent Collections
|1. (WO2017039331) HETEROARYL COMPOUNDS AND THEIR USE AS THERAPEUTIC DRUGS|
|Applicants:||DONG-A SOCIO HOLDINGS CO., LTD.
KIM, Jin Kwan
RYU, Ki Moon
PARK, Seong Jin
JANG, Mi Yeon
|Title:||HETEROARYL COMPOUNDS AND THEIR USE AS THERAPEUTIC DRUGS|
The present invention provides heterocyclic compounds, the stereoisomer thereof, the enantiomer thereof, or the pharmaceutically acceptable salt, which are capable of modulating the activity of Mer receptor tyrosine kinase (MERTK). This invention also provides pharmaceutical compositions thereof, methods to prepare the said compounds, and the use of such compounds as a medicament. The present invention is directed to MERTK inhibitory compounds with marked potency, thereby having an outstanding potential for a pharmaceutical intervention of cancer and any other diseases related to MERTK dysregulation.