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1. (WO2017039316) MICROASPIRATION-BASED LUNG WINDOW APPARATUS FOR OBTAINING MICROSCOPIC IMAGE OF IN VIVO LUNG TISSUE AND METHOD FOR OBTAINING IMAGE USING SAME

Pub. No.:    WO/2017/039316    International Application No.:    PCT/KR2016/009720
Publication Date: Fri Mar 10 00:59:59 CET 2017 International Filing Date: Thu Sep 01 01:59:59 CEST 2016
IPC: A61B 5/08
A61B 5/00
G02B 21/00
G02B 21/36
Applicants: MEDICINAL BIOCONVERGENCE RESEARCH CENTER
재단법인 의약바이오컨버젼스연구단
KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY
한국과학기술원
Inventors: KIM, Pil Han
김필한
PARK, Inwon
박인원
KIM, Sunghoon
김성훈
Title: MICROASPIRATION-BASED LUNG WINDOW APPARATUS FOR OBTAINING MICROSCOPIC IMAGE OF IN VIVO LUNG TISSUE AND METHOD FOR OBTAINING IMAGE USING SAME
Abstract:
Disclosed are a microaspiration-based lung window apparatus for obtaining a microscopic image of in vivo lung tissue and a method for obtaining an image using same. The present invention provides a lung window apparatus comprising: an open window which has the upper part and lower part open, a cover glass disposed on the upper part and lung tissue coming in contact with the lower part; an aspiration tube which extends from one side of the open window to an aspiration apparatus and enables the inside of the open window to be in a vacuum state; and a tilting mount placing unit which extends from one side of the open window and has placed thereon a tilting mount that enables the cover glass and an object lens of a confocal microscope system to stay parallel to each other. The present invention enables maintaining of physiological respiration and circulation of an animal without interference as well as stable acquisition of cell-level and molecular level microscopic images of in vivo lung tissue.