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1. (WO2017039107) NEW XYLENE-BASED AMPHIPATHIC COMPOUND AND USE THEREOF

Pub. No.:    WO/2017/039107    International Application No.:    PCT/KR2016/003929
Publication Date: Fri Mar 10 00:59:59 CET 2017 International Filing Date: Sat Apr 16 01:59:59 CEST 2016
IPC: C07H 15/00
C07H 3/04
C07C 15/107
C07K 1/14
G01N 1/28
G01N 33/68
Applicants: INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY ERICA CAMPUS
한양대학교 에리카산학협력단
Inventors: CHAE, Pil Seok
채필석
CHO, Kyung Ho
조경호
Title: NEW XYLENE-BASED AMPHIPATHIC COMPOUND AND USE THEREOF
Abstract:
The present invention relates to a xylene-based amphipathic compound, a method for preparing same, and a method for extracting, solubilizing, stabilizing, or crystallizing membrane proteins by using said compound. By using the xylene-based compound according to the present invention, membrane proteins can be stably kept in an aqueous solution for a long period of time and thus can be utilized in the analysis of the function and structure thereof. The analysis of the structure and function of membrane proteins is one of the fields that currently receive the most attention in biology and chemistry, and thus can be applied to protein structure research, which is closely related to the development of new drugs.