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1. (WO2017039096) PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING METABOLIC DISORDERS, CONTAINING SPHINGOSINE-1-PHOSPHATE OR MATERIAL INCREASING EXPRESSION OF SPHK2

Pub. No.:    WO/2017/039096    International Application No.:    PCT/KR2016/002410
Publication Date: Fri Mar 10 00:59:59 CET 2017 International Filing Date: Fri Mar 11 00:59:59 CET 2016
IPC: A61K 31/133
A61K 31/661
A61K 48/00
A61K 8/68
A61Q 19/00
G01N 33/50
Applicants: GACHON UNIVERSITY OF INDUSTRY-ACADEMIC COOPERATION FOUNDATION
가천대학교 산학협력단
Inventors: PARK, Tae Sik
박태식
SHIM, Soon Mi
심순미
LEE, Su Yeon
이수연
MAENG, Hyo Jin
맹효진
Title: PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING METABOLIC DISORDERS, CONTAINING SPHINGOSINE-1-PHOSPHATE OR MATERIAL INCREASING EXPRESSION OF SPHK2
Abstract:
The present invention provides: a pharmaceutical composition, a food composition and a cosmetic composition for preventing or treating metabolic disorders, containing any one selected from the group consisting of sphingosine-1-phosphate, a sphingosine-1-phosphate promoter and a material increasing the expression of Sphk2; and a method for screening for a material for preventing or treating metabolic disorders by using the mechanism. The pharmaceutical composition, the food composition and the cosmetic composition of the present invention can be useful as a pharmaceutical composition, a food composition and a cosmetic composition for preventing or treating metabolic disorders, particularly, a fatty liver such as nonalcoholic fatty liver, dyslipidemia such as hyperlipidemia or hypertriglyceridemia, and obesity, and the screening method using the mechanism can be useful as a method for screening for a material for preventing or treating metabolic disorders.