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1. (WO2017038997) AGENT FOR ENHANCING IMMUNITY TO CANCER BY USING Allergin-1 ANTAGONIST
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Pub. No.: WO/2017/038997 International Application No.: PCT/JP2016/075887
Publication Date: 09.03.2017 International Filing Date: 02.09.2016
IPC:
A61K 39/395 (2006.01) ,A61K 38/00 (2006.01) ,A61K 45/00 (2006.01) ,A61K 45/06 (2006.01) ,A61P 35/00 (2006.01) ,A61P 35/02 (2006.01) ,A61P 37/04 (2006.01) ,A61P 43/00 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
395
Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
45
Medicinal preparations containing active ingredients not provided for in groups A61K31/-A61K41/132
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
45
Medicinal preparations containing active ingredients not provided for in groups A61K31/-A61K41/132
06
Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35
Antineoplastic agents
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35
Antineoplastic agents
02
specific for leukemia
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
37
Drugs for immunological or allergic disorders
02
Immunomodulators
04
Immunostimulants
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
43
Drugs for specific purposes, not provided for in groups A61P1/-A61P41/108
Applicants:
小野薬品工業株式会社 ONO PHARMACEUTICAL CO., LTD. [JP/JP]; 大阪府大阪市中央区道修町二丁目1番5号 1-5, Doshomachi 2-chome, Chuo-ku, Osaka-shi, Osaka 5418526, JP
Inventors:
柴山 史朗 SHIBAYAMA, Shiro; JP
有馬 宏 ARIMA, Hiroshi; JP
新坊 拓也 SIMBO, Takuya; JP
Agent:
青木 篤 AOKI, Atsushi; JP
石田 敬 ISHIDA, Takashi; JP
福本 積 FUKUMOTO, Tsumoru; JP
古賀 哲次 KOGA, Tetsuji; JP
渡辺 陽一 WATANABE, Yoichi; JP
武居 良太郎 TAKEI, Ryotaro; JP
佐々木 貴英 SASAKI, Takahide; JP
Priority Data:
2015-17365903.09.2015JP
2016-13837413.07.2016JP
Title (EN) AGENT FOR ENHANCING IMMUNITY TO CANCER BY USING Allergin-1 ANTAGONIST
(FR) AGENT DESTINÉ À AMÉLIORER L'IMMUNITÉ CONTRE LE CANCER EMPLOYANT UN ANTAGONISTE D'Allergine-1
(JA) Allergin-1アンタゴニストによるがん免疫増強剤
Abstract:
(EN) The present invention addresses the problem of providing a medicinal agent for suppressing the progression and recurrence of cancer and/or for treating cancer, the medicinal agent comprising a novel active ingredient having the effect of enhancing immunity to cancer. This Allergin-1 antagonist has the effect of enhancing immunity to cancer, and can be used for suppressing the progression and recurrence of cancer and/or for treating cancer. In particular, this Allergin-1 antagonist is useful for treating cancer patients for whom the therapeutic effects of anti-tumor immunotherapeutic agent are insufficient, or useful for cancer treatments in combination with anti-cancer drugs.
(FR) La présente invention concerne un agent médicinal destiné à réduire l'évolution et la récurrence du cancer et/ou à traiter le cancer, l'agent médicinal comprenant un nouveau principe actif présentant un effet d'amélioration l'immunité contre le cancer. Cet antagoniste de l'allergine-1 a pour effet d'améliorer l'immunité contre le cancer, et peut être utilisé pour réduire l'évolution et la récurrence du cancer et/ou pour traiter le cancer. En particulier, cet antagoniste de l'allergine-1 est utile pour traiter des patients atteints d'un cancer chez lesquels les effets thérapeutiques d'un agent immunothérapeutique antitumoral sont insuffisants, ou il est utile pour des traitements du cancer en combinaison avec des médicaments anticancéreux.
(JA) 本発明の課題は、がん免疫増強作用を有する新規な有効成分からなるがんの進行抑制、再発抑制および/または治療を目的とする薬剤を提供することにある。本発明にかかるAllergin-1アンタゴニストは、がん免疫増強作用を有しており、がんの進行抑制、再発抑制および/または治療のために使用することができる。特に、腫瘍免疫治療薬による治療効果が十分ではないがん患者を対象とする治療、あるいは抗がん剤との併用によるがん治療に有用である。
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)