Search International and National Patent Collections

1. (WO2017038986) METHOD FOR PRODUCING RECOMBINANT PROTEIN

Pub. No.:    WO/2017/038986    International Application No.:    PCT/JP2016/075848
Publication Date: Fri Mar 10 00:59:59 CET 2017 International Filing Date: Sat Sep 03 01:59:59 CEST 2016
IPC: C12P 21/08
C07K 1/22
C12N 5/10
C12P 21/02
Applicants: MOCHIDA PHARMACEUTICAL CO., LTD.
持田製薬株式会社
Inventors: NONOMURA Kazuhiko
野々村 和彦
NAITOH Katsuki
内藤 克紀
HIROSE Jiro
広瀬 二郎
Title: METHOD FOR PRODUCING RECOMBINANT PROTEIN
Abstract:
Provided is a method for producing tocilizumab, the method including: the culture of animal cells that secrete tocilizumab in a medium containing soybean hydrolysate, which improves the degree of galactosylation of the sugar chains of a recombinant protein; and the isolation of tocilizumab from the culture broth obtained by culturing the animal cells.