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1. (WO2017038870) UREA DERIVATIVE AND USE THEREOF
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Pub. No.: WO/2017/038870 International Application No.: PCT/JP2016/075495
Publication Date: 09.03.2017 International Filing Date: 31.08.2016
IPC:
C07C 381/00 (2006.01) ,A61K 31/17 (2006.01) ,A61P 35/00 (2006.01) ,A61P 35/04 (2006.01) ,A61P 43/00 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
C
ACYCLIC OR CARBOCYCLIC COMPOUNDS
381
Compounds containing carbon and sulfur and having functional groups not covered by groups C07C301/-C07C337/142
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
16
Amides, e.g. hydroxamic acids
17
having the group N-C(O)-N or N-C(S)-N, e.g. urea, thiourea, carmustine
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35
Antineoplastic agents
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35
Antineoplastic agents
04
specific for metastasis
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
43
Drugs for specific purposes, not provided for in groups A61P1/-A61P41/108
Applicants:
東レ株式会社 TORAY INDUSTRIES, INC. [JP/JP]; 東京都中央区日本橋室町2丁目1番1号 1-1, Nihonbashi-Muromachi 2-chome, Chuo-ku, Tokyo 1038666, JP
Inventors:
筒井 英之 TSUTSUI, Hideyuki; JP
沖村 慶一 OKIMURA, Keiichi; JP
宇田川 秀二 UDAGAWA, Syuji; JP
戒能 美枝 KAINO, Mie; JP
目黒 裕之 MEGURO, Hiroyuki; JP
關谷 由美子 SEKIYA, Yumiko; JP
Priority Data:
2015-17001331.08.2015JP
Title (EN) UREA DERIVATIVE AND USE THEREOF
(FR) DÉRIVÉ D'URÉE ET UTILISATION ASSOCIÉE
(JA) 尿素誘導体及びその用途
Abstract:
(EN) The purpose of the present invention is to provide a compound having an inhibition activity against discoidin domain receptor 1. The present invention provides a urea derivative represented by the formula and a pharmacologically acceptable salt thereof.
(FR) La présente invention vise à fournir un composé ayant une activité d'inhibition contre le récepteur à domaine discoïdine 1. La présente invention concerne par conséquent un dérivé d'urée représenté par la formule et un sel pharmacologiquement acceptable de celui-ci.
(JA) 本発明は、ディスコイジンドメイン受容体1に対して阻害活性を有する化合物を提供することを目的としている。本発明は、下式に代表される尿素誘導体又はその薬理学的に許容される塩を提供する。
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)