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1. (WO2017038861) FREE-POLYUNSATURATED-FATTY-ACID-CONTAINING COMPOSITION AND METHOD FOR MANUFACTURING SAME
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Pub. No.: WO/2017/038861 International Application No.: PCT/JP2016/075445
Publication Date: 09.03.2017 International Filing Date: 31.08.2016
IPC:
C11C 3/00 (2006.01) ,A23D 9/007 (2006.01) ,A61K 31/201 (2006.01) ,A61K 31/202 (2006.01) ,A61P 3/06 (2006.01) ,A61P 7/02 (2006.01) ,A61P 9/10 (2006.01) ,A61P 25/28 (2006.01) ,A61P 29/00 (2006.01) ,A61P 35/00 (2006.01) ,A61P 37/08 (2006.01) ,C07C 57/12 (2006.01) ,C07C 69/58 (2006.01)
C CHEMISTRY; METALLURGY
11
ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
C
FATTY ACIDS FROM FATS, OILS OR WAXES; CANDLES; FATS, OILS OR FATTY ACIDS BY CHEMICAL MODIFICATION OF FATS, OILS, OR FATTY ACIDS OBTAINED THEREFROM
3
Fats, oils, or fatty acids by chemical modification of fats, oils, or fatty acids obtained therefrom
[IPC code unknown for A23D 9/07]
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
185
Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
19
Carboxylic acids, e.g. valproic acid
20
having a carboxyl group bound to an acyclic chain of seven or more carbon atoms, e.g. stearic, palmitic or arachidic acid
201
having one or two double bonds, e.g. oleic or linoleic acid
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
185
Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
19
Carboxylic acids, e.g. valproic acid
20
having a carboxyl group bound to an acyclic chain of seven or more carbon atoms, e.g. stearic, palmitic or arachidic acid
202
having three or more double bonds, e.g. linolenic acid
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
3
Drugs for disorders of the metabolism
06
Antihyperlipidemics
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
7
Drugs for disorders of the blood or the extracellular fluid
02
Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
9
Drugs for disorders of the cardiovascular system
10
for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25
Drugs for disorders of the nervous system
28
for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
29
Non-central analgesic, antipyretic or antiinflammatory agents, e.g antirheumatic agents; Non-steroidal antiinflammatory drugs (NSAIDs)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35
Antineoplastic agents
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
37
Drugs for immunological or allergic disorders
08
Antiallergic agents
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
C
ACYCLIC OR CARBOCYCLIC COMPOUNDS
57
Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
02
with only carbon-to-carbon double bonds as unsaturation
03
Monocarboxylic acids
12
Straight chain carboxylic acids containing eighteen carbon atoms
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
C
ACYCLIC OR CARBOCYCLIC COMPOUNDS
69
Esters of carboxylic acids; Esters of carbonic or haloformic acids
52
Esters of acyclic unsaturated carboxylic acids having the esterified carboxyl group bound to an acyclic carbon atom
533
Monocarboxylic acid esters having only one carbon-to-carbon double bond
58
Esters of straight chain acids with eighteen carbon atoms in the acid moiety
Applicants:
日本水産株式会社 NIPPON SUISAN KAISHA, LTD. [JP/JP]; 東京都港区西新橋一丁目3番1号 3-1, Nishi-Shinbashi 1-chome, Minato-ku, Tokyo 1058676, JP
Inventors:
山口 秀明 YAMAGUCHI Hideaki; JP
土居崎 信滋 DOISAKI Nobushige; JP
佐藤 誠造 SATO Seizo; JP
小菅 雄平 KOSUGE Yuhei; JP
Agent:
アインゼル・フェリックス=ラインハルト EINSEL Felix-Reinhard; JP
前川 純一 MAEKAWA Junichi; JP
二宮 浩康 NINOMIYA Hiroyasu; JP
上島 類 UESHIMA Rui; JP
醍醐 美知子 DAIGO Michiko; JP
Priority Data:
2015-17085631.08.2015JP
Title (EN) FREE-POLYUNSATURATED-FATTY-ACID-CONTAINING COMPOSITION AND METHOD FOR MANUFACTURING SAME
(FR) COMPOSITION CONTENANT DES ACIDES GRAS POLYINSATURÉS LIBRES ET SON PROCÉDÉ DE FABRICATION
(JA) 遊離多価不飽和脂肪酸含有組成物及びその製造方法
Abstract:
(EN) Provided is a free-polyunsaturated-fatty-acid-containing composition that has a total metal content of 0.1 ppm or less and that comprises at least one free polyunsaturated fatty acid having 20 or more carbon atoms, in an amount that is at least 80.0% of the amount of fatty acids in the composition; and a method for manufacturing a free-polyunsaturated-fatty-acid-containing composition, comprising: providing a raw material composition containing at least one polyunsaturated fatty acid having 20 or more carbon atoms; implementing a hydrolysis treatment on a reaction solution prepared by combining the provided raw material composition, a lower alcohol, water having a total metal content of 0.01 ppm or less, and an alkali catalyst; and limiting the contact between the reaction composition and the metal after the hydrolysis treatment so that the product T [cm2 × days] of the contact surface area [cm2] and the contact time [days] between every 1 g of the composition and the metal is 100 or less.
(FR) La présente invention concerne une composition contenant des acides gras polyinsaturés libres qui a une teneur totale en métaux de 0,1 ppm ou moins et qui comprend au moins un acide gras polyinsaturé libre ayant 20 atomes de carbone ou plus, en une quantité qui est au moins 80,0 % de la quantité d’acides gras dans la composition ; et un procédé de fabrication d’une composition contenant des acides gras polyinsaturés libres, comprenant : la fourniture d’une composition de matière première contenant au moins un acide gras polyinsaturé comportant 20 atomes de carbone ou plus ; la mise en œuvre d’un traitement d’hydrolyse sur une solution de réaction préparée par combinaison de la composition de matière première fournie, un alcool inférieur, de l’eau ayant une teneur totale en métaux de 0,01 ppm ou moins, et un catalyseur alcalin ; et la limitation du contact entre la composition de réaction et le métal après le traitement d’hydrolyse de sorte que le produit T [cm2 × jours] de l’aire de surface de contact [cm2] et le temps de contact [jours] entre chaque 1 g de la composition et du métal soit de 100 ou moins.
(JA) 含有量が組成物中の脂肪酸の80.0%以上である、少なくとも1つの炭素数20以上の遊離多価不飽和脂肪酸を含み、金属の合計含有量が0.1ppm以下である遊離多価不飽和脂肪酸含有組成物と;少なくとも1つの炭素数20以上の多価不飽和脂肪酸を含む原料組成物を用意すること、用意された原料組成物、低級アルコール、金属の合計含有量が0.01ppm以下の水、及びアルカリ触媒を組み合わせて調製される反応液に対して、加水分解処理を行うこと、加水分解処理後の反応組成物と金属との接触を、1gあたりの組成物と金属との接触表面積[cm]と接触時間[日]との積T[cm×日]が、100以下となるように制限すること、を含む、遊離多価不飽和脂肪酸含有組成物の製造方法が提供される。
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)