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1. (WO2017038799) UREASE ACTIVITY INHIBITOR

Pub. No.:    WO/2017/038799    International Application No.:    PCT/JP2016/075280
Publication Date: Fri Mar 10 00:59:59 CET 2017 International Filing Date: Wed Aug 31 01:59:59 CEST 2016
IPC: A61K 38/00
A61K 35/50
A61K 36/48
A61K 36/82
A61K 36/899
A61K 36/8998
A61K 38/16
A61K 38/17
A61P 1/02
A61P 1/04
A61P 13/02
A61P 17/00
A61P 43/00
Applicants: SUNTORY HOLDINGS LIMITED
サントリーホールディングス株式会社
Inventors: FUKIZAWA, Shinya
富貴澤 伸哉
KODA, Hirofumi
好田 裕史
Title: UREASE ACTIVITY INHIBITOR
Abstract:
Provided is a urease activity inhibitor having as an active ingredient a cyclic dipeptide or a salt thereof. This urease activity inhibitor: has characteristics such that the cyclic dipeptide contained is difficult to decompose in the stomach or duodenum; inhibits urease activity within the body; has the potential for, for example, a gastric mucosal protective effect, a suppressive effect on urinary calculus formation, or a prophylactic or therapeutic effect on diseases caused by urease-producing microorganisms; and can be used with the expectation of a suppressive effect on ammonia odor from feces and urine and a preventative effect on diaper rash, a deodorizing effect for livestock, and a suppressive effect on halitosis or body odor.