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1. (WO2017038281) MIRABEGRON-CONTAINING TABLET, METHOD FOR PRODUCING MIRABEGRON-CONTAINING PHARMACEUTICAL PREPARATION AND METHOD FOR PRODUCING MIRABEGRON-CONTAINING GRANULATED PRODUCT
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2017/038281 International Application No.: PCT/JP2016/071140
Publication Date: 09.03.2017 International Filing Date: 19.07.2016
IPC:
A61K 31/426 (2006.01) ,A61K 9/14 (2006.01) ,A61K 9/20 (2006.01) ,A61K 47/32 (2006.01) ,A61K 47/38 (2006.01) ,A61P 13/10 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
41
having five-membered rings with two or more ring hetero atoms, at least one of which is nitrogen, e.g. tetrazole
425
Thiazoles
426
1,3-Thiazoles
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
14
Particulate form, e.g. powders
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
20
Pills, lozenges or tablets
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
30
Macromolecular compounds
32
Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
30
Macromolecular compounds
36
Polysaccharides; Derivatives thereof
38
Cellulose; Derivatives thereof
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
13
Drugs for disorders of the urinary system
10
of the bladder
Applicants:
沢井製薬株式会社 SAWAI PHARMACEUTICAL CO., LTD. [JP/JP]; 大阪府大阪市淀川区宮原5丁目2番30号 2-30, Miyahara 5-chome, Yodogawa-ku, Osaka City, Osaka 5320003, JP
Inventors:
柳 敏宏 YANAGI Toshihiro; JP
野沢 健児 NOZAWA Kenji; JP
梅村 香織 UMEMURA Kaori; JP
有村 雅敏 ARIMURA Masatoshi; JP
高田 亜紀子 TAKADA Akiko; JP
Agent:
特許業務法人高橋・林アンドパートナーズ TAKAHASHI, HAYASHI AND PARTNER PATENT ATTORNEYS, INC.; 東京都大田区蒲田5-24-2 損保ジャパン蒲田ビル9階 Sonpo Japan Kamata Building 9F, 5-24-2 Kamata, Ota-ku, Tokyo 1440052, JP
Priority Data:
2015-17166601.09.2015JP
Title (EN) MIRABEGRON-CONTAINING TABLET, METHOD FOR PRODUCING MIRABEGRON-CONTAINING PHARMACEUTICAL PREPARATION AND METHOD FOR PRODUCING MIRABEGRON-CONTAINING GRANULATED PRODUCT
(FR) COMPRIMÉ CONTENANT DU MIRABÉGRON, PROCÉDÉ DE PRODUCTION D'UNE PRÉPARATION PHARMACEUTIQUE CONTENANT DU MIRABÉGRON ET PROCÉDÉ DE PRODUCTION D'UN PRODUIT SOUS FORME GRANULÉE CONTENANT DU MIRABÉGRON
(JA) ミラベグロン含有錠剤、ミラベグロン含有製剤の製造方法及びミラベグロン含有造粒物の製造方法
Abstract:
(EN) [Problem] To provide a mirabegron-containing tablet which retains the amorphous state of mirabegron after long-term storage; a mirabegron-containing pharmaceutical preparation capable of retaining mirabegron purity by preventing analog formation during storage; a method for producing a mirabegron-containing pharmaceutical preparation; and a method for producing a mirabegron-containing granulated product. [Solution] According to one embodiment of the present invention, provided is a mirabegron-containing pharmaceutical preparation, characterized in comprising mirabegron, and hypromellose and polyvinyl pyrrolidone. The mirabegron-containing pharmaceutical preparation may comprise a spray-dried granulated product comprising the mirabegron and the hypromellose and the polyvinyl pyrrolidone.
(FR) [Problème] Il s'agit de produire un comprimé contenant du mirabégron qui reste à l'état amorphe après un stockage de longue durée; une préparation pharmaceutique contenant du mirabégron qui conserve la pureté du mirabégron en empêchant la formation d'analogues pendant le stockage; un procédé de production d'une préparation pharmaceutique contenant du mirabégron; et un procédé de production d'un produit sous forme granulée contenant du mirabégron. [Solution] Selon une forme de réalisation de la présente invention, on a produit une préparation pharmaceutique contenant du mirabégron caractérisée en ce qu'elle comprend du mirabégron ainsi que de l'hypromellose et de la polyvinylepyrrolidone. La préparation pharmaceutique contenant du mirabégron peut comprendre un produit sous forme granulée séché par pulvérisation comprenant le mirabégron ainsi que l'hypromellose et la polyvinylepyrrolidone.
(JA) 【課題】長期間保存後にもミラベグロンの非晶質状態を維持したミラベグロン含有錠剤を提供する。また、保存時に類縁物質の生成を抑制し、ミラベグロンの純度を維持可能なミラベグロン含有製剤、ミラベグロン含有製剤の製造方法及びミラベグロン含有造粒物の製造方法を提供する。 【解決手段】本発明に一実施形態によると、ミラベグロンと、ヒプロメロース及びポリビニルピロリドンとを含むことを特徴とする、ミラベグロン含有製剤が提供される。前記ミラベグロン含有製剤は、前記ミラベグロンと、前記ヒプロメロース及び前記ポリビニルピロリドンとを含む噴霧乾燥造粒物を含んでもよい。
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)