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1. (WO2017038101) DEVELOPMENT OF DIETARY THERAPY IN CANCER
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Pub. No.: WO/2017/038101 International Application No.: PCT/JP2016/004023
Publication Date: 09.03.2017 International Filing Date: 02.09.2016
IPC:
A61K 45/00 (2006.01) ,A61K 31/22 (2006.01) ,A61K 31/7016 (2006.01) ,A61P 35/00 (2006.01) ,A61P 43/00 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
45
Medicinal preparations containing active ingredients not provided for in groups A61K31/-A61K41/132
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
21
Esters, e.g. nitroglycerine, selenocyanates
215
of carboxylic acids
22
of acyclic acids, e.g. pravastatin
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
70
Carbohydrates; Sugars; Derivatives thereof
7016
Disaccharides, e.g. lactose, lactulose
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35
Antineoplastic agents
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
43
Drugs for specific purposes, not provided for in groups A61P1/-A61P41/108
Applicants:
国立大学法人大阪大学 OSAKA UNIVERSITY [JP/JP]; 大阪府吹田市山田丘1番1号 1-1, Yamadaoka, Suita-shi, Osaka 5650871, JP
株式会社明治 MEIJI CO., LTD. [JP/JP]; 東京都中央区京橋二丁目2番1号 2-1, Kyobashi 2-chome, Chuo-ku, Tokyo 1048306, JP
Inventors:
萩原 圭祐 HAGIHARA, Keisuke; JP
芦田 欣也 ASHIDA, Kinya; JP
殿内 秀和 TONOUCHI, Hidekazu; JP
中村 健太郎 NAKAMURA, Kentaro; JP
Agent:
山本 秀策 YAMAMOTO, Shusaku; JP
森下 夏樹 MORISHITA, Natsuki; JP
▲駒▼谷 剛志 KOMATANI, Takeshi; JP
飯田 貴敏 IIDA, Takatoshi; JP
石川 大輔 ISHIKAWA, Daisuke; JP
山本 健策 YAMAMOTO, Kensaku; JP
Priority Data:
2015-17519804.09.2015JP
Title (EN) DEVELOPMENT OF DIETARY THERAPY IN CANCER
(FR) DÉVELOPPEMENT DE THÉRAPIE DIÉTÉTIQUE DANS LE CANCER
(JA) 癌における食事療法の開発
Abstract:
(EN) The invention provides new compositions or combinations thereof for the treatment of cancer. More specifically, the invention provides compositions or combinations thereof for cancer treatment including a high-fat diet. Specifically, the high-fat diet is characterized by having approximately 120 g/day or more, or approximately 70% or more of the total daily energy, from fat, based on a real weight of 50 kg. The diet is preferably a carbohydrate-restricted high-fat diet, and more preferably provided by a ketone formula and/or MCT oil. The dietary therapy by a high-fat diet of the present invention is provided along with surgical treatment, chemotherapy or radiation therapy, or combinations thereof.
(FR) La présente invention concerne de nouvelles compositions ou des combinaisons de celles-ci pour le traitement du cancer. Plus spécifiquement, l’invention concerne des compositions ou des combinaisons de celles-ci pour le traitement du cancer comprenant un régime alimentaire riche en matières grasses. Spécifiquement, le régime riche en matières grasses est caractérisé en ce qu’il comporte approximativement 120 g/jour ou plus, ou approximativement 70 % ou plus du total de l’énergie journalière totale, de matières grasses, sur la base d’un poids réel de 50 kg. Le régime alimentaire est, de préférence, un régime alimentaire limité en glucides et riche en matières grasses, et plus préférablement fourni par une formule cétonique et/ou une huile MCT. La thérapie diététique par un régime riche en matières grasses de la présente invention est fournie conjointement avec un traitement chirurgical, une chimiothérapie ou une radiothérapie, ou des combinaisons de ceux-ci.
(JA) 本発明は新たながんの治療のための組成物またはその組合せを提供する。より詳細には、本発明は、高脂肪食を含む、がんを処置するための組成物またはその組合せを提供する。具体的には、前記高脂肪食は、脂肪を、実質体重50kgを基準とした場合に1日あたり約120g以上、または1日の総エネルギーの約70%以上とすることを特徴とし、好ましくは、糖質制限高脂肪食であり、さらに好ましくはケトンフォーミュラおよび/またはMCTオイルで提供される。本発明の高脂肪食による食事療法は、手術療法、化学療法もしくは放射線療法またはそれらの組合せとともに提供される。
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)