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1. (WO2017037812) PATCH PREPARATION CONTAINING ACID SCAVENGER

Pub. No.:    WO/2017/037812    International Application No.:    PCT/JP2015/074552
Publication Date: Fri Mar 10 00:59:59 CET 2017 International Filing Date: Sun Aug 30 01:59:59 CEST 2015
IPC: A61K 31/485
A61K 47/10
A61K 47/12
A61K 47/14
A61K 47/18
A61K 47/22
A61K 9/70
A61P 25/04
Applicants: MEDRX CO., LTD.
株式会社メドレックス
Inventors: HAMAMOTO, Hidetoshi
濱本 英利
TANIMOTO, Takahiro
谷本 高広
Title: PATCH PREPARATION CONTAINING ACID SCAVENGER
Abstract:
The purpose of the present invention is to provide a patch preparation which uses a basic drug acid addition salt as a raw material and which has excellent skin permeability of the drug. This patch preparation is formed by providing an adhesive layer on one side of a support body, wherein the adhesive layer contains a basic drug, a fatty acid ionic liquid and a potassium salt, wherein said potassium salt is generated in the adhesive by a reaction between the acid addition salt of the basic drug and a compound capable of generating potassium ions. An opioid analgesic is an example of the basic drug, and hydrochloride is an example of the acid addition salt.