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1. (WO2017037661) COMPOSITIONS AND METHODS FOR THE TREATMENT OF PARKINSON'S DISEASE
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Pub. No.: WO/2017/037661 International Application No.: PCT/IB2016/055259
Publication Date: 09.03.2017 International Filing Date: 02.09.2016
IPC:
A61K 31/16 (2006.01) ,A61K 31/385 (2006.01) ,A61K 31/185 (2006.01) ,A61P 25/16 (2006.01) ,C07C 57/48 (2006.01) ,C07C 233/49 (2006.01) ,C07C 339/04
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
16
Amides, e.g. hydroxamic acids
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
38
having sulfur as a ring hetero atom
385
having two or more sulfur atoms in the same ring
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
185
Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25
Drugs for disorders of the nervous system
14
for treating abnormal movements, e.g. chorea, dyskinesia
16
Anti-Parkinson drugs
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
C
ACYCLIC OR CARBOCYCLIC COMPOUNDS
57
Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
46
containing six-membered aromatic rings and other rings, e.g. cyclohexylphenylacetic acid
48
having unsaturation outside the aromatic rings
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
C
ACYCLIC OR CARBOCYCLIC COMPOUNDS
233
Carboxylic acid amides
01
having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
45
having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
46
with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
49
having the carbon atom of the carboxamide group bound to a carbon atom of an acyclic unsaturated carbon skeleton
[IPC code unknown for C07C 339/04]
Applicants:
CELLIXBIO PRIVATE LIMITED [IN/IN]; Plot No.1177b, Road No.56 Jubilee Hills Hyderabad 500 081, IN
Inventors:
KANDULA, Mahesh; IN
Agent:
KHURANA & KHURANA, ADVOCATES & IP ATTORNEYS; E-13, UPSIDC, Site-IV, Behind-Grand Venice Kasna Road, Greater Noida, National Capital Region Uttar Pradesh 201310, IN
Priority Data:
20164101911302.06.2016IN
4630/CHE/201502.09.2015IN
Title (EN) COMPOSITIONS AND METHODS FOR THE TREATMENT OF PARKINSON'S DISEASE
(FR) COMPOSITIONS ET MÉTHODES POUR LE TRAITEMENT DE LA MALADIE DE PARKINSON
Abstract:
(EN) The invention relates to the compounds of formula I, formula II and formula III or its pharmaceutical acceptable salts, as well as polymorphs, solvates, enantiomers, stereoisomers and hydrates thereof. The pharmaceutical compositions comprising an effective amount of compounds of formula I, formula II and formula III, and methods for treating or preventing Parkinson's diseasemay be formulated for oral, buccal, rectal, topical, transdermal, transmucosal, intravenous, parenteral administration, syrup, or injection. Such compositions may be used to treatment or management of Parkinson's diseasesuch as Parkinson's disease, scleroderma, restless leg syndrome, hypertension and gestational hypertension.
(FR) La présente invention concerne des composés de formule (I), (II) et (III) ou leurs sels de qualité pharmaceutique, ainsi que leurs polymorphes, solvates, énantiomères, stéréoisomères et hydrates. L'invention concerne également des compositions pharmaceutiques comprenant une quantité efficace de composés de formule I, II et III, et des méthodes de traitement ou de prévention de la maladie de Parkinson, lesdites compositions pouvant être formulées pour une administration par voie orale, buccale, rectale, topique, transdermique, transmucosale, intraveineuse, parentérale, en sirop ou par injection. Ces compositions peuvent être utilisées pour le traitement ou la prise en charge de la maladie de Parkinson, de la sclérodermie, du syndrome des jambes sans repos, de l'hypertension et de l'hypertension gestationnelle.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)