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1. (WO2017037639) A PROCESS FOR THE PREPARATION OF XYLENE LINKED CYCLAM COMPOUNDS
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Pub. No.: WO/2017/037639 International Application No.: PCT/IB2016/055215
Publication Date: 09.03.2017 International Filing Date: 01.09.2016
IPC:
C07D 257/02 (2006.01) ,C07D 519/00 (2006.01)
[IPC code unknown for C07D 257/02][IPC code unknown for C07D 519]
Applicants:
FRESENIUS KABI ONCOLOGY LTD. [IN/IN]; B – 310, Som Datt Chambers – I, Bhikaji Cama Place New Delhi 110066, IN
Inventors:
SINGH, Hemant Kumar; IN
KUMAR, Sandeep; IN
SONAVANE, Ghanashyam Madhukar; IN
HANDA, Vishal; IN
GUPTA, Chandan Kumar; IN
SANGHANI, Sunil; IN
SIVAIAH, Potru; IN
LAHIRI, Saswata; IN
CABRI, Walter; IT
GUPTA, Nitin; IN
Agent:
TIWARI, Prachi; IN
Priority Data:
2758/DEL/201502.09.2015IN
Title (EN) A PROCESS FOR THE PREPARATION OF XYLENE LINKED CYCLAM COMPOUNDS
(FR) PROCÉDÉ DE PRÉPARATION DE COMPOSÉS DE CYCLAME LIÉS AU XYLÈNE
Abstract:
(EN) The present invention relates to an improved process for the preparation of xylene linked cyclam compounds. More particularly the invention provides a process for preparation of high purity plerixafor which does not involve the use of expensive chemicals, hazardous reagents or tedious purification techniques. Invention also provides novel intermediate useful for preparation of desired compound in high purity.
(FR) La présente invention concerne un procédé amélioré pour la préparation de composés de cyclame liés au xylène. Plus particulièrement, l'invention concerne un procédé de préparation de plérixafor de pureté élevée qui n'implique pas l'utilisation de produits chimiques coûteux, de réactifs dangereux ou de techniques de purification fastidieuses. L'invention concerne également de nouveaux intermédiaires utiles pour la préparation du composé voulu avec une pureté élevée.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)