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1. (WO2017037539) MODULATION OF THE PHOSPHOLIPASE A2-ACTIVATING PROTEIN FOR TREATMENT OF MYELIN RELATED DISEASES
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Pub. No.: WO/2017/037539 International Application No.: PCT/IB2016/001350
Publication Date: 09.03.2017 International Filing Date: 02.09.2016
IPC:
A61K 48/00 (2006.01) ,C12N 15/01 (2006.01) ,G06F 19/22 (2011.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
48
Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15
Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
01
Preparation of mutants without inserting foreign genetic material therein; Screening processes therefor
G PHYSICS
06
COMPUTING; CALCULATING; COUNTING
F
ELECTRIC DIGITAL DATA PROCESSING
19
Digital computing or data processing equipment or methods, specially adapted for specific applications
10
Bioinformatics, i.e. methods or systems for genetic or protein-related data processing in computational molecular biology
22
for sequence comparison involving nucleotides or amino acids, e.g. homology search, motif or SNP [Single-Nucleotide Polymorphism] discovery or sequence alignment
Applicants:
FALIK ZACCAI, Tzipora, C. [IL/IL]; IL (US)
THE HEALTH CORPORATION OF THE GALILEE MEDICAL CENTER [IL/IL]; Naharyia, IL (AllExceptUS)
Inventors:
FALIK ZACCAI, Tzipora, C.; IL
Priority Data:
62/213,33902.09.2015US
Title (EN) MODULATION OF THE PHOSPHOLIPASE A2-ACTIVATING PROTEIN FOR TREATMENT OF MYELIN RELATED DISEASES
(FR) MODULATION DE LA PROTÉINE ACTIVANT LA PHOSPHOLIPASE A2 POUR LE TRAITEMENT DE MALADIES ASSOCIÉES À LA MYÉLINE
Abstract:
(EN) The present invention provides a method of treating a subject afflicted with a white matter disorder comprising administering to the subject an agent that induces the activity of the Phospholipase A2-Activating Protein (PLAA) pathway in the subject.
(FR) La présente invention concerne un procédé de traitement d'un sujet atteint d'une affection de la substance blanche, comprenant l'administration au sujet d'un agent qui induit l'activité de la voie de la protéine activant la Phospholipase A2 (PLAA) chez le sujet.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)