Search International and National Patent Collections

1. (WO2017037108) SYNTHETIC NICHE MATRICES FOR STEM CELL CULTURE

Pub. No.:    WO/2017/037108    International Application No.:    PCT/EP2016/070500
Publication Date: Fri Mar 10 00:59:59 CET 2017 International Filing Date: Thu Sep 01 01:59:59 CEST 2016
IPC: A61L 27/56
C12N 5/00
Applicants: POLITECNICO DI MILANO
CONSIGLIO NAZIONALE DELLE RICERCHE
FONDAZIONE CASSA DI RISPARMIO DELLE PROVINCE LOMBARDE
Inventors: RAIMONDI, Manuela Teresa
CERULLO, Giulio
OSELLAME, Roberto
REMUZZI, Andrea
Title: SYNTHETIC NICHE MATRICES FOR STEM CELL CULTURE
Abstract:
The present invention relates to a supermatrix of synthetic niches comprising at least two matrices of niches wherein each matrix comprises n x m niches and wherein the distance (d) between a matrix and the other is greater than zero and wherein in each matrix every synthetic niche has one or more walls in common with the others synthetic niches of the matrix. A support for the culture of cells that includes at least one supermatrix and the use of said supermatrix or support for the in vitro culture of cells, in particular stem cells, or for the in vivo implant in a subject in order to promote tissue or organ regeneration through cell repopulation are also within the scope of the present invention.