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1. (WO2017037013) MEANS AND METHODS FOR PRODUCTION OF ORGANIC COMPOUNDS
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Pub. No.: WO/2017/037013 International Application No.: PCT/EP2016/070307
Publication Date: 09.03.2017 International Filing Date: 29.08.2016
IPC:
C12P 7/10 (2006.01) ,C12P 7/44 (2006.01) ,C12N 9/02 (2006.01)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
P
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
7
Preparation of oxygen-containing organic compounds
02
containing a hydroxy group
04
acyclic
06
Ethanol, i.e. non-beverage
08
produced as by-product or from waste or cellulosic material substrate
10
substrate containing cellulosic material
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
P
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
7
Preparation of oxygen-containing organic compounds
40
containing a carboxyl group
44
Polycarboxylic acids
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
9
Enzymes, e.g. ligases (6.); Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating, or purifying enzymes
02
Oxidoreductases (1.), e.g. luciferase
Applicants:
UNIVERSITAET DES SAARLANDES [DE/DE]; Campus Saarbruecken 66123 Saarbruecken, DE
Inventors:
VAN DUUREN, Jozef; DE
STOLZENBERGER, Jessica; DE
KOHLSTEDT, Michael; DE
STARCK, Sören; DE
SELZER, Mirjam; DE
FRITZ, Michel; FR
HOELTZEN, Heike; DE
RICHTER, Rudolf; DE
WITTMANN, Christoph; DE
Agent:
WEINZIERL, Gerhard; DE
SCHIWECK, Wolfram Dr.; DE
KOCH, Andreas Dr.; DE
Priority Data:
15002547.628.08.2015EP
9282208.09.2015LU
Title (EN) MEANS AND METHODS FOR PRODUCTION OF ORGANIC COMPOUNDS
(FR) MOYENS ET PROCÉDÉS POUR LA PRODUCTION DE COMPOSÉS ORGANIQUES
Abstract:
(EN) The present invention relates to the field of biotechnology. It involves the decomposition and conversion of organic educts, in particular biomass feedstock, lignin, guaiacol; p-coumaryl alcohol; coniferyl alcohol; sinapyl alcohol; cresol; phenol; catechol; polysaccharides; cellulose hemicellulose; xylose; glucose; fructose; proteins; amino acids; triacylglycerides and/or fatty acids into useful organic compounds with the help of biocatalysts. A method of producing an organic product comprises i) fluid-assisted decomposition of an organic educt under sub- or supercritical conditions ii) obtaining an intermediate product from step i) iii) subjecting the intermediate product to biocatalytic conversion, by contacting the intermediate product obtained in step ii) with a biocatalyst, wherein said biocatalyst is a host cell selected from the group consisting of bacteria, yeast, filamentous fungi, cyanobacteria, algae, and plant cells. Further, a host cell is provided herein that can advantageously be employed in the methods of the invention.
(FR) La présente invention concerne le domaine de la biotechnologie. Elle a trait à la décomposition et la conversion de produits de départ organiques (en particulier matière première de type biomasse ; lignine ; gaïacol ; alcool p-coumarylique ; alcool coniférylique ; alcool synapylique ; crésol ; phénol ; catéchol ; polysaccharides ; cellulose, hémicellulose ; xylose ; glucose ; fructose ; protéines ; acides aminés ; triglycérides et/ou acides gras) en composés organiques utiles, à l'aide de biocatalyseurs. Un procédé de production d'un produit organique comprend : i) la décomposition assistée par fluide d'un produit de départ organique dans des conditions sous- ou supercritiques ; ii) l'obtention d'un produit intermédiaire issu de l'étape i) ; iii) la soumission du produit intermédiaire à une conversion biocatalytique, par mise en contact du produit intermédiaire obtenu à l'étape ii) avec un biocatalyseur, ledit biocatalyseur étant une cellule hôte choisie dans le groupe constitué de bactéries, de levures, de champignons filamenteux, d'algues, de cyanobactéries et de cellules de plantes. L'invention concerne en outre une cellule hôte qui peut être avantageusement utilisée dans les procédés de l'invention.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)