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Pub. No.: WO/2017/036926 International Application No.: PCT/EP2016/070118
Publication Date: 09.03.2017 International Filing Date: 25.08.2016
Chapter 2 Demand Filed: 20.06.2017
A23L 33/105 (2016.01)
[IPC code unknown for A23L 33/105]
UNILEVER PLC [GB/GB]; a company registered in England and Wales under company no. 41424 of Unilever House 100 Victoria Embankment London Greater London EC4Y 0DY, GB (AE, AG, AU, BB, BH, BN, BW, BZ, CA, CY, EG, GB, GD, GH, GM, IE, IL, IN, KE, KN, LC, LK, LS, MT, MW, MY, NA, NG, NZ, OM, PG, QA, RW, SA, SC, SD, SG, SL, SZ, TT, TZ, UG, VC, ZA, ZM, ZW)
UNILEVER N.V. [NL/NL]; Weena 455 3013 AL Rotterdam, NL (AL, AM, AO, AT, AZ, BA, BE, BF, BG, BJ, BR, BY, CF, CG, CH, CI, CL, CM, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, ES, FI, FR, GA, GE, GN, GQ, GR, GT, GW, HN, HR, HU, ID, IR, IS, IT, JP, KG, KM, KP, KR, KZ, LA, LR, LT, LU, LV, LY, MA, MC, MD, ME, MG, MK, ML, MN, MR, MX, MZ, NE, NI, NL, NO, PA, PE, PH, PL, PT, RO, RS, RU, SE, SI, SK, SM, SN, ST, SV, SY, TD, TG, TH, TJ, TM, TN, TR, UA, UZ, VN)
CONOPCO, INC., D/B/A UNILEVER [US/US]; 800 Sylvan Avenue AG West, S. Wing Englewood Cliffs, New Jersey 07632, US (US)
FOWLER, Mark, Ian; GB
WANG, Huijun; CN
WARNER, Guy, Jonathan; GB
Priority Data:
(EN) Foods or meals high in available carbohydrate such as sucrose or starch increase postprandial blood glucose concentrations. According to Node et al. (Cardiovascular diabetology, 8, 23 (2009)), repeated high post-prandial plasma glucose "spikes" are associated with an increased risk of developing type II diabetes. Unregulated glycemic excursions are undesirable, and any reduction or "blunting" of the post-prandial glucose concentration in blood is potentially beneficial. This invention relates to an edible composition for delay of intestinal glucose uptake through synergistic inhibition of both active sodium glucose co-transporter 1 (SGLT1 ) and passive glucose transporter 2 (GLUT2) leading to flattening or blunting of the post-prandial glucose peak. Thus in a first aspect of the invention, an edible composition provided in the form of a single serving of one or more unit dosages comprising a combination of 2 to 200 mg of at least one homoisoflavonoid and 20 to 2000 mg of at least one flavonoid monoglucoside, and salts thereof.
(FR) Les aliments ou les repas à forte teneur en glucides tels que le saccharose ou l'amidon augmentent la glycémie postprandiale. Selon Node et al. (Cardiovascular diabetology, 8, 23 (2009)), la répétition de fortes poussées postprandiales de glucose plasmique est associée à un risque accru de développer un diabète de type II. De tels pics de glycémie non régulés ne sont pas souhaitables, et toute réduction ou atténuation de la glycémie postprandiale est potentiellement bénéfique. L'invention concerne donc une composition comestible destinée à retarder l'assimilation intestinale du glucose par inhibition synergique aussi bien du co-transporteur actif 1 de sodium-glucose (SGTL1) que du transporteur passif de glucose (GLUT2), ce qui conduit à un aplatissement ou à une réduction du pic de glucose postprandial. Ainsi, dans un premier aspect, l'invention concerne une composition comestible qui se présente sous la forme d'une seule portion d'une ou de plusieurs doses unitaires comprenant une combinaison de 2 à 200 mg d'au moins un homoisoflavonoïde et de 20 à 2000 mg d'au moins un flavonoïde monoglycoside, et des sels de ceux-ci.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)