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1. (WO2017036903) IMPROVED VITAMIN PRODUCTION

Pub. No.:    WO/2017/036903    International Application No.:    PCT/EP2016/070049
Publication Date: Fri Mar 10 00:59:59 CET 2017 International Filing Date: Fri Aug 26 01:59:59 CEST 2016
IPC: C07K 14/32
C07K 14/33
C12P 25/00
C12N 1/36
C12N 15/00
Applicants: DSM IP ASSETS B.V.
Inventors: HANS, Michael
HOHMANN, Hans-Peter
LEHMANN, Martin
POTOT, Sebastien
Title: IMPROVED VITAMIN PRODUCTION
Abstract:
The present invention provides an improved biotechnological production of riboflavin (also referred herein as vitamin B2) using genetically engineered microorganisms, in particular microorganism selected from Bacillus, such as e.g. Bacillus subtilis. Using said modified microorganisms, the yield of riboflavin 5 production could be increased by at least 5%. The present invention relates to modified microorganisms, processes to generate said modified microorganisms and the use thereof for production of riboflavin.