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|1. (WO2017036805) A SEPARATION MATRIX AND A METHOD OF SEPARATING ANTIBODIES|
|Applicants:||GE HEALTHCARE BIOPROCESS R&D AB
|Inventors:||LACKI, Karol, Maciej
|Title:||A SEPARATION MATRIX AND A METHOD OF SEPARATING ANTIBODIES|
The invention discloses a separation matrix comprised of porous spherical particles to which antibody-binding protein ligands have been covalently immobilized, wherein the density of said ligands is in the range of 10.5 - 15 mg/ml and the volume-weighted median diameter of said particles is in the range of 30 - 55 µm. The invention further discloses a method of separation of antibodies by affinity chromatography which employs the said separation matrix within a chromatography column.