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1. (WO2017036404) CARBOXY SUBSTITUTED (HETERO) AROMATIC RING DERIVATIVES AND PREPARATION METHOD AND USES THEREOF

Pub. No.:    WO/2017/036404    International Application No.:    PCT/CN2016/097660
Publication Date: Fri Mar 10 00:59:59 CET 2017 International Filing Date: Thu Sep 01 01:59:59 CEST 2016
IPC: C07D 215/02
C07D 261/20
C07D 249/18
C07D 263/54
C07D 209/04
C07D 235/08
C07D 237/28
C07D 291/08
A61K 31/33
A61K 31/404
A61P 3/10
Applicants: SUNSHINE LAKE PHARMA CO., LTD.
Inventors: YANG, Xinye
HUANG, Changwei
MA, Facheng
ZHANG, Ji
WANG, Xiaojun
ZHANG, Yingjun
Title: CARBOXY SUBSTITUTED (HETERO) AROMATIC RING DERIVATIVES AND PREPARATION METHOD AND USES THEREOF
Abstract:
Carboxy-substituted (hetero)aryl derivatives, pharmaceutical compositions comprising these compounds, and methods of preparing such compounds and compositions are provided. The compounds or compositions are useful in inhibiting xanthine oxidase and urate anion transporter 1, and also can be used in the treatment or prevention of diseases associated with high blood uric acid level in mammals, especially humans.