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1. (WO2017036356) CRYSTAL FORM OF FLUDARABINE PHOSPHAT, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF
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Pub. No.: WO/2017/036356 International Application No.: PCT/CN2016/096878
Publication Date: 09.03.2017 International Filing Date: 26.08.2016
IPC:
C07H 19/20 (2006.01) ,C07H 19/16 (2006.01) ,C07H 1/06 (2006.01) ,A61P 35/00 (2006.01)
[IPC code unknown for C07H 19/20][IPC code unknown for C07H 19/16][IPC code unknown for C07H 1/06][IPC code unknown for A61P 35]
Applicants:
浙江海正药业股份有限公司 ZHEJIANG HISUN PHARMACEUTICAL CO., LTD. [CN/CN]; 中国浙江省台州市 椒江区外沙路46号 46 Waisha Road Jiaojiang District Taizhou, Zhejiang 318000, CN
Inventors:
杨志清 YANG, Zhiqing; CN
张亮 ZHANG, Liang; CN
张相洋 ZHANG, Xiangyang; CN
施珍娟 SHI, Zhenjuan; CN
苏迪 SU, Di; CN
骆红英 LUO, Hongying; CN
傅德进 FU, Dejin; CN
Agent:
北京邦信阳专利商标代理有限公司 BOSS&YOUNG PATENT AND TRADEMARK LAW OFFICE; 中国北京市 朝阳区建国门外大街永安东里甲3号通用时代国际中心A座5层 5/F., Tower A, GT International Center, Jia 3 Yongandongli Jianguomenwai Ave., ChaoyangDistrict Beijing 100022, CN
Priority Data:
201510540739.628.08.2015CN
Title (EN) CRYSTAL FORM OF FLUDARABINE PHOSPHAT, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF
(FR) FORME CRISTALLINE DE PHOSPHATE DE FLUDARABINE, PROCÉDÉ DE PRÉPARATION DE CELLE-CI, ET APPLICATION DE CELLE-CI
(ZH) 磷酸氟达拉滨的晶型及其制备方法和用途
Abstract:
(EN) Provided are a new crystal form of Fludarabine Phosphat, a preparation method therefor, a pharmaceutical composition containing same, and an application thereof in preparing medicine. Crystal forms I and II of the Fludarabine Phosphat have excellent properties in terms of solubleness, dissolution rate, chemical stability, and processing adaptability.
(FR) L'invention concerne une nouvelle forme cristalline de phosphate de fludarabine, un procédé de préparation associé, une composition pharmaceutique contenant celle-ci, et une application de celle-ci dans la préparation de médicaments. Les formes cristallines I et II du phosphate de fludarabine présentent d'excellentes propriétés en termes de pouvoir de dissolution, vitesse de dissolution, stabilité chimique et adaptabilité au traitement.
(ZH) 提供一种磷酸氟达拉滨的新晶型及其制备方法、含有其的药物组合物及其制药用途。所述磷酸氟达拉滨的晶型I和II在溶解性、溶解速度、化学稳定性和加工适应性方面具有优异的性质。
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Chinese (ZH)
Filing Language: Chinese (ZH)