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1. (WO2017036284) COMBINED APPLICATION OF DIRECT OR INDIRECT AGONIST OF EPAC AND ONCOLYTIC VIRUS
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Pub. No.: WO/2017/036284 International Application No.: PCT/CN2016/094314
Publication Date: 09.03.2017 International Filing Date: 10.08.2016
IPC:
A61K 45/00 (2006.01) ,A61K 35/76 (2015.01) ,A61P 35/00 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
45
Medicinal preparations containing active ingredients not provided for in groups A61K31/-A61K41/132
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35
Medicinal preparations containing material or reaction products thereof with undetermined constitution
66
Materials from micro-organisms
76
Viruses
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35
Antineoplastic agents
Applicants:
广州威溶特医药科技有限公司 GUANGZHOU VIROTECH PHARMACEUTICAL CO., LTD. [CN/CN]; 中国广东省广州市 广州高新技术产业开发区科学城揽月路3号广州国际企业孵化器G区416房 Room 416, Building G, No. 3 Lanyue Road, Guangzhou Science City Guangzhou, Guangdong 510663, CN
Inventors:
颜光美 YAN, Guangmei; CN
李凯 LI, Kai; CN
肖晓 XIAO, Xiao; CN
胡骏 HU, Jun; CN
梁剑开 LIANG, Jiankai; CN
林园 LIN, Yuan; CN
张海鹏 ZHANG, Haipeng; CN
邱鹏新 QIU, Pengxin; CN
朱文博 ZHU, Wenbo; CN
银巍 YIN, Wei; CN
林穗珍 LIN, Suizhen; CN
Agent:
广州市天河区倪律专利代理事务所(普通合伙) WINGUAN PATENT AND TRADEMARK ATTORNEYS; 中国广东省广州市 天河区思成路23号607 607, 23 Sicheng Road, Tianhe District Guangzhou, Guangdong 510663, CN
Priority Data:
201510563433.206.09.2015CN
Title (EN) COMBINED APPLICATION OF DIRECT OR INDIRECT AGONIST OF EPAC AND ONCOLYTIC VIRUS
(FR) APPLICATION COMBINÉE D'AGONISTE DIRECT OU INDIRECT D'EPAC ET DE VIRUS ONCOLYTIQUE
(ZH) Epac直接或间接激动剂与溶瘤病毒的联合应用
Abstract:
(EN) Disclosed are a pharmaceutical composition containing a direct or indirect agonist of Epac and an oncolytic virus, medication set, and the use thereof in the preparation of medication for treating tumors, in particular, tumors insensitive to the oncolytic virus. Also disclosed is a method of producing an oncolytic virus in-vitro.
(FR) La présente invention concerne une composition pharmaceutique contenant un agoniste direct ou indirect d'Epac et un virus oncolytique, l’ensemble de préparation du médicament et l’utilisation de celui-ci dans la préparation du médicament pour le traitement de tumeurs, en particulier, les tumeurs insensibles au virus oncolytique. L'invention concerne également un procédé de production d'un virus oncolytique in vitro.
(ZH) 一种包含Epac直接或间接激动剂和溶瘤病毒的药物组合物、药品套装,及其在制备治疗肿瘤、特别是对所述溶瘤病毒不敏感的肿瘤药物中的用途。一种体外生产溶瘤病毒的方法。
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Chinese (ZH)
Filing Language: Chinese (ZH)